Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 20/20 | 0.81 |
| ▸ | RPS6KB1 | P23443 | 19/20 | 0.81 |
| ▸ | AURKB | Q96GD4 | 10/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16162051 | 0.92 | AURKA (0.80) | AURKARPS6KB1AURKB | |
| SCHEMBL16162060 | 0.91 | AURKA (0.81) | AURKARPS6KB1AURKB | |
| SCHEMBL16161899 | 0.91 | AURKA (0.82) | AURKARPS6KB1AURKB | |
| SCHEMBL666665 | 0.89 | AURKA (1.00) | AURKARPS6KB1AURKB | |
| SCHEMBL16162016 | 0.89 | AURKA (0.79) | AURKARPS6KB1AURKB | |
| SCHEMBL16161983 | 0.85 | AURKA (0.84) | AURKARPS6KB1AURKB | |
| SCHEMBL16161914 | 0.84 | AURKA (0.82) | AURKARPS6KB1AURKB | |
| SCHEMBL16161871 | 0.83 | AURKA (0.81) | AURKARPS6KB1AURKB | |
| SCHEMBL3804003 | 0.82 | AURKA (1.00) | AURKARPS6KB1AURKB | |
| SCHEMBL664456 | 0.82 | AURKA (1.00) | AURKARPS6KB1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396307-B1 | NOVEL AMINO AZAHETEROCYCLIC CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2014-10-15 | — | — | EP | claimed |