Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.57 |
| ▸ | CNR1 | P21554 | 9/20 | 0.57 |
| ▸ | ACHE | P22303 | 7/20 | 0.57 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19790225 | 0.89 | CNR2 (0.62) | CNR2CNR1ACHEBCHEL3MBTL1 | |
| SCHEMBL15081324 | 0.87 | CNR2 (0.63) | CNR2CNR1ACHEBCHEF2RL3 | |
| SCHEMBL15081382 | 0.82 | CNR2 (0.58) | CNR2CNR1ACHEL3MBTL1MAPT | |
| SCHEMBL14923635 | 0.81 | CNR2 (0.55) | CNR2CNR1ACHEF2RL3L3MBTL1 | |
| SCHEMBL14923441 | 0.81 | CNR2 (0.52) | CNR2CNR1ACHEBCHEF2RL3 | |
| SCHEMBL15081472 | 0.80 | CNR2 (0.54) | CNR2CNR1ACHEF2RL3L3MBTL1 | |
| SCHEMBL15081320 | 0.80 | CNR2 (0.43) | CNR2CNR1ACHEBCHEMAPT | |
| SCHEMBL3380069 | 0.79 | CNR2 (0.56) | CNR2CNR1ACHEF2RL3L3MBTL1 | |
| SCHEMBL15081380 | 0.78 | CNR2 (0.52) | CNR2CNR1ACHEBCHEF2RL3 | |
| SCHEMBL14923443 | 0.77 | CNR2 (0.56) | CNR2CNR1ACHEF2RL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799431-B1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORP (JP) | 2018-01-24 | — | — | EP | disclosed |
| CN-104024226-B | Novel nicotinamide derivative or salt thereof | FUJIFILM CORP. (JP) | 2016-06-01 | — | — | CN | disclosed |
| US-9051310-B2 | Nicotinamide derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2015-06-09 | — | — | US | disclosed |
| US-9051310-B2 | Nicotinamide derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2015-06-09 | — | — | US | disclosed |
| EP-2799431-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM Corporation (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-20140309225-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2014-10-16 | — | — | US | disclosed |
| US-20140309225-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2014-10-16 | — | — | US | disclosed |
| US-20140309225-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2014-10-16 | — | — | US | disclosed |
| CN-104024226-A | Novel nicotinamide derivative or salt thereof | FUJIFILM CORP | 2014-09-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309225-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | SYK, BTK, NOX4 | CNR2 1045/4885CNR1 821/4885ACHE 3135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.