SCHEMBL16164643

SCHEMBL16164643

Clc1cc(Oc2cc(Cl)c(OCC(Br)CBr)c(Cl)c2)cc(Cl)c1OCC(Br)CBr

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
TSHR P16473 1/20 0.32
HSP90AA1 P07900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28424724 0.88 ALDH1A1 (0.40) ALDH1A1HSP90AA1
SCHEMBL16164286 0.84 ALDH1A1 (0.63) ALDH1A1TSHR
SCHEMBL16164287 0.82 ALDH1A1 (0.49) ALDH1A1TSHR
SCHEMBL5087482 0.82 ALDH1A1 (0.49) ALDH1A1TSHR
SCHEMBL16163824 0.81 ALDH1A1 (0.47) ALDH1A1TSHR
SCHEMBL5428065 0.79 ALDH1A1 (0.50) ALDH1A1TSHR
SCHEMBL16164068 0.79 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL28424378 0.79 ALDH1A1 (0.50) ALDH1A1TSHR
SCHEMBL16163630 0.78 ALDH1A1 (0.39) ALDH1A1HSP90AA1
SCHEMBL5426562 0.78 ALDH1A1 (0.74) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106795345-B Fiber-reinforced flame-retardant polypropylene resin composition and molded article using same 日本聚丙烯株式会社 2021-05-11 CN disclosed
CN-107075201-B Fiber-reinforced flame-retardant polypropylene resin composition and molded article using same 日本聚丙烯株式会社 2020-06-23 CN disclosed
EP-3202841-B1 FIBER-REINFORCED FLAME-RETARDANT POLYPROPYLENE RESIN COMPOSITION AND MOLDED ARTICLE USING THE SAME JAPAN POLYPROPYLENE CORP (JP) 2019-05-08 EP disclosed
US-9321897-B2 Thermoplastic resin composition and toilet components made therefrom JAPAN POLYPROPYLENE CORPORATION (JP) 2016-04-26 US disclosed
US-20140309350-A1 THERMOPLASTIC RESIN COMPOSITION AND TOILET COMPONENTS MADE THEREFROM JAPAN POLYPROPYLENE CORPORATION (JP) 2014-10-16 US disclosed