Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FER | P16591 | 6/20 | 0.46 |
| ▸ | SYK | P43405 | 14/20 | 0.44 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.43 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16165750 | 0.92 | FER (0.46) | FERSYKMAPK3MAPK1KCNH2 | |
| SCHEMBL16164436 | 0.91 | FER (0.45) | FERSYKMAPK3MAPK1KCNH2 | |
| SCHEMBL16164685 | 0.90 | FER (0.55) | FERSYKMAPK3MAPK1KCNH2 | |
| SCHEMBL16165499 | 0.89 | SYK (0.49) | FERSYKMAPK3MAPK1KCNH2 | |
| SCHEMBL16169284 | 0.89 | SYK (0.55) | FERSYK | |
| SCHEMBL16164546 | 0.86 | SYK (0.51) | SYKKCNH2 | |
| SCHEMBL16164970 | 0.86 | FER (0.45) | FERSYKMAPK3MAPK1KCNH2 | |
| SCHEMBL16165041 | 0.86 | FER (0.49) | FERSYKMAPK3MAPK1KCNH2 | |
| SCHEMBL16165395 | 0.85 | FER (0.50) | FERSYK | |
| SCHEMBL16165034 | 0.85 | SYK (0.54) | FERSYKMAPK3MAPK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799431-B1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORP (JP) | 2018-01-24 | — | — | EP | disclosed |
| US-9051310-B2 | Nicotinamide derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2015-06-09 | — | — | US | disclosed |
| EP-2799431-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM Corporation (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-20140309225-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2014-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309225-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | SYK, BTK, NOX4 | FER 441/4885SYK 1/4885MAPK3 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.