Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 3/20 | 0.35 |
| ▸ | OXTR | P30559 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16166157 | 0.83 | KMT2A (0.47) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL16173941 | 0.73 | KMT2A (0.51) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL16166004 | 0.73 | KMT2A (0.46) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL16166174 | 0.73 | MYC (0.50) | KMT2AMEN1NPC1RAB9ASPR | |
| SCHEMBL18404054 | 0.73 | KMT2A (0.37) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL16173947 | 0.72 | KMT2A (0.45) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL16166012 | 0.71 | KMT2A (0.44) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL16166048 | 0.71 | KMT2A (0.46) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL16166020 | 0.70 | MAPT (0.54) | KMT2ANPC1RAB9ASPRMAPK13 | |
| SCHEMBL16166317 | 0.69 | KMT2A (0.44) | KMT2AMEN1NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9750253-B2 | Pesticidally active substituted pyridyl carboxamides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| US-9750253-B2 | Pesticidally active substituted pyridyl carboxamides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| EP-2984083-B1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-25 | — | — | EP | disclosed |
| US-20160050924-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-25 | — | — | US | disclosed |
| US-20160050924-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-25 | — | — | US | disclosed |
| EP-2984083-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | Syngenta Participations AG (CH) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014166795-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-16 | — | — | WO | disclosed |
| WO-2014166795-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160050924-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | CBR3, CBR1, CYCS | KMT2A 1902/4885MEN1 361/4885NPC1 3544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.