Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 5/20 | 0.55 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL8466588 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL9247678 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL1263331 | 1.00 | — | — | |
| Bicarbonate SCHEMBL3397287 | 0.95 | CA4 (0.50) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL17963004 | 0.95 | CA4 (0.50) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL15794084 | 0.95 | CA4 (0.50) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL28174367 | 0.95 | CA4 (0.50) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL2420 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1332437 | 0.94 | — | — | |
| Bicarbonate SCHEMBL2558186 | 0.94 | CA4 (0.60) | CA1CA2CA9CA4FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984135-B1 | A COMPOSITE HAVING ACOUSTIC PROPERTIES | UPM KYMMENE CORP (FI) | 2022-03-09 | — | — | EP | disclosed |
| US-10414074-B2 | Method to manufacture a composite product with micro contoured surface layer | UPM-KYMMENE CORPORATION (FI) | 2019-09-17 | — | — | US | disclosed |
| US-9928821-B2 | Composite having acoustic properties, manufacturing the composite, a component comprising a composite, manufacturing the component and uses thereof | UPM-KYMMENE CORPORATION (FI) | 2018-03-27 | — | — | US | disclosed |
| US-20160082625-A1 | A COMPOSITE STRUCTURE WITH SURFACE ROUGHNESS | UPM-KYMMENE CORPORATION (FI) | 2016-03-24 | — | — | US | disclosed |
| EP-2996853-A1 | A COMPOSITE STRUCTURE WITH SURFACE ROUGHNESS | UPM-Kymmene Corporation (FI) | 2016-03-23 | — | — | EP | disclosed |
| US-20160063984-A1 | A COMPOSITE HAVING ACOUSTIC PROPERTIES, MANUFACTURING THE COMPOSITE, A COMPONENT COMPRISING A COMPOSITE, MANUFACTURING THE COMPONENT AND USES THEREOF | UPM-KYMMENE CORPORATION (FI) | 2016-03-03 | — | — | US | disclosed |
| EP-2984135-A1 | A COMPOSITE HAVING ACOUSTIC PROPERTIES, MANUFACTURING THE COMPOSITE, A COMPONENT COMPRISING A COMPOSITE, MANUFACTURING THE COMPONENT AND USES THEREOF | UPM-Kymmene Corporation (FI) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014184418-A1 | A COMPOSITE STRUCTURE WITH SURFACE ROUGHNESS | UPM-KYMMENE CORPORATION (FI) | 2014-11-20 | — | — | WO | disclosed |
| WO-2014167167-A1 | A COMPOSITE HAVING ACOUSTIC PROPERTIES, MANUFACTURING THE COMPOSITE, A COMPONENT COMPRISING A COMPOSITE, MANUFACTURING THE COMPONENT AND USES THEREOF | UPM-KYMMENE CORPORATION (FI) | 2014-10-16 | — | — | WO | disclosed |