SCHEMBL16166643

SCHEMBL16166643

CNC(=O)N(N)S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1163614 0.73
SCHEMBL16701285 0.73
SCHEMBL1770998 0.73
SCHEMBL28372436 0.69
SCHEMBL29105525 0.67
SCHEMBL10930536 0.67 NQO1 (0.35)
SCHEMBL11637182 0.67
SCHEMBL20073458 0.65 NQO1 (0.34)
SCHEMBL5416201 0.65
SCHEMBL483009 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4653436-A1 HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF GUANGZHOU YUFAN NANTU BIOTECHNOLOGIES CO., LTD (CN) 2025-11-26 EP disclosed
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF SCHRÖDINGER, INC. 2025-08-21 US disclosed
US-12325697-B2 CBL-B modulators and uses thereof NIMBUS CLIO, INC. (US) 2025-06-10 US disclosed
US-20250163038-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. 2025-05-22 US disclosed
WO-2024153240-A1 HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF 珠海宇繁生物科技有限责任公司 2024-07-25 WO disclosed
WO-2024112692-A1 CASITAS B-LINEAGE LYMPHOMA PROTOONCOGENE B (CBL-B) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS, INC. (US) 2024-05-30 WO disclosed
EP-4359381-A1 CBL-B MODULATORS AND USES THEREOF Nimbus Clio, Inc. (US) 2024-05-01 EP disclosed
CN-117858865-A CBL-B modulators and uses thereof 林伯士克莱奥公司 2024-04-09 CN disclosed
CN-117858707-A CBL-B modulators and uses thereof 林伯士克莱奥公司 2024-04-09 CN disclosed
EP-4319756-A1 CBL-B MODULATORS AND USES THEREOF Nimbus Clio, Inc. (US) 2024-02-14 EP disclosed
US-9926294-B2 Pesticidally active heterocyclic derivatives with sulphur containing substituents SYNGENTA PARTICIPATIONS AG (CH) 2018-03-27 US disclosed
WO-2018041729-A2 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2018-03-08 WO disclosed
US-20170217928-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2017-08-03 US disclosed
CN-106488914-A Tool with sulfur-bearing substituent kills harmful organism active heterocycles derivative 先正达参股股份有限公司 2017-03-08 CN disclosed
EP-3122740-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS Syngenta Participations AG (CH) 2017-02-01 EP disclosed
US-20170000132-A1 BENZOXABOROLE FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2017-01-05 US disclosed
EP-3086644-A1 BENZOXABOROLE FUNGICIDES Syngenta Participations AG (CH) 2016-11-02 EP disclosed
WO-2015144826-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2015-10-01 WO disclosed
WO-2015097237-A1 BENZOXABOROLE FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2015-07-02 WO disclosed
WO-2014167133-A1 FUNGICIDES COMPRISING BORON SYNGENTA PARTICIPATIONS AG (CH) 2014-10-16 WO disclosed