⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1163614 | 0.67 | — | — | |
| SCHEMBL857558 | 0.67 | — | — | |
| SCHEMBL16166643 | 0.65 | — | — | |
| SCHEMBL7642756 | 0.64 | — | — | |
| SCHEMBL29105525 | 0.62 | — | — | |
| SCHEMBL10930536 | 0.62 | NQO1 (0.35) | — | |
| SCHEMBL8387988 | 0.60 | — | — | |
| SCHEMBL20073458 | 0.60 | NQO1 (0.34) | — | |
| SCHEMBL483009 | 0.60 | — | — | |
| SCHEMBL43202 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027143-A1 | Novel substituted 2,3-benzodiazepine derivatives | IVAX DRUG RESEARCH INSTITUTE, LTD. (HU) | 2007-02-01 | — | — | US | disclosed |
| EP-1592673-A4 | NOVEL SUBSTITUTED 2,3-BENZODIAZEPINE DERIVATIVES | IVAX DRUG RES INST LTD (HU) | 2006-10-25 | — | — | EP | disclosed |
| EP-1592673-A2 | NOVEL SUBSTITUTED 2,3-BENZODIAZEPINE DERIVATIVES | Ivax Institute for Drug Research, Ltd. (HU) | 2005-11-09 | — | — | EP | disclosed |
| US-6858605-B2 | Substituted 2,3-benzodiazepine derivatives | IVAX DRUG RESEARCH INSTITUTE, LTD. (HU) | 2005-02-22 | — | — | US | disclosed |
| WO-2004069197-A2 | NOVEL SUBSTITUTED 2,3-BENZODIAZEPINE DERIVATIVES | IVAX CORPORATION (US) | 2004-08-19 | — | — | WO | disclosed |
| US-20040152693-A1 | Novel substituted 2,3-benzodiazepine derivatives | IVAX DRUG RESEARCH INSTITUTE, LTD. | 2004-08-05 | — | — | US | disclosed |