Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.53 |
| ▸ | MEN1 | O00255 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 6/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | APAF1 | O14727 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25C | P30307 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601020 | 1.00 | MAPT (0.53) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL25649956 | 0.77 | ADORA2A (0.55) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL29530 | 0.76 | KMT2A (0.55) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL16167389 | 0.74 | NQO1 (0.53) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL3418850 | 0.72 | MEN1 (0.55) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL14657071 | 0.72 | MAPT (0.68) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL29362140 | 0.72 | MAPT (0.68) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL27157150 | 0.72 | MAPT (0.68) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL29892465 | 0.72 | MAPT (0.68) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL6650819 | 0.68 | MEN1 (0.55) | MAPTKMT2AMEN1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107375260-B | Novel compounds and compositions for targeting cancer stem cells | 北京强新生物科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| EP-2983790-A2 | METHODS FOR TREATING CANCER | Boston Biomedical, Inc. (US) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014169078-A2 | METHODS FOR TREATING CANCER | BOSTON BIOMEDICAL, INC. (US) | 2014-10-16 | — | — | WO | disclosed |