SCHEMBL1616725

SCHEMBL1616725

COCCCOC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4173353 0.94
SCHEMBL5541778 0.93 ALDH1A1 (0.32)
SCHEMBL4283071 0.92 ALDH1A1 (0.44)
SCHEMBL4285238 0.92 ALDH1A1 (0.44)
SCHEMBL27016234 0.92 ALDH1A1 (0.44)
SCHEMBL5544331 0.87 ALDH1A1 (0.37)
SCHEMBL5388661 0.85 CYP3A4 (0.34)
SCHEMBL5545162 0.85 ALDH1A1 (0.40)
SCHEMBL7675153 0.85 CYP3A4 (0.34)
SCHEMBL5538963 0.85 ALDH1A1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530650-B2 2, 5-diamino-substituted pyrido [4, 3-D] pyrimidines as autotaxin inhibitors against cancer MERCK PATENT GMBH (DE) 2013-09-10 US claimed
EP-2352732-B1 2,5-DIAMINO-SUBSTITUTED PYRIDO[4, 3-d]PYRIMIDINES AS AUTOTAXIN INHIBITORS AGAINST CANCER MERCK PATENT GMBH (DE) 2013-02-20 EP claimed
US-20110237583-A1 2, 5-DIAMINO-SUBSTITUTED PYRIDO [4, 3-D] PYRIMIDINES AS AUTOTAXIN INHIBITORS AGAINST CANCER MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 2011-09-29 US claimed
EP-2352732-A1 2, 5-DIAMINO-SUBSTITUTED PYRIDO Ý4, 3-D¨PYRIMIDINES AS AUTOTAXIN INHIBITORS AGAINST CANCER Merck Patent GmbH (DE) 2011-08-10 EP claimed
WO-2010063352-A1 2, 5-DIAMINO-SUBSTITUTED PYRIDO [4, 3-D] PYRIMIDINES AS AUTOTAXIN INHIBITORS AGAINST CANCER MERCK PATENT GMBH (DE) 2010-06-10 WO claimed
CN-114466893-B Polyester film for window covering, and polyester film laminate for window covering 三菱化学株式会社 2024-03-01 CN disclosed
US-20220228096-A1 Cell Scaffold Material, Cell Culture Support, and Cell Culture Method SHOWA DENKO MATERIALS CO., LTD. (JP) 2022-07-21 US disclosed
CN-114466893-A Polyester film for window attachment and polyester film laminate for window attachment 三菱化学株式会社 2022-05-10 CN disclosed
EP-3992276-A1 CELL SCAFFOLD MATERIAL, CELL CULTURING SUPPORT, AND CELL CULTURING METHOD Showa Denko Materials Co., Ltd. (JP) 2022-05-04 EP disclosed
CN-114051530-A Cell scaffold material, cell culture support, and method for culturing cells 昭和电工材料株式会社 2022-02-15 CN disclosed
US-20210309619-A1 ISOXAZOLIN-5-ONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2021-10-07 US disclosed
CN-106444285-B Photosensitive resin composition for color filter and application thereof 奇美实业股份有限公司 2021-09-10 CN disclosed
EP-0207581-A2 Thiazolidine derivatives, their preparation and use SANKYO COMPANY LIMITED (JP) 1987-01-07 EP disclosed
US-4603138-A ANTIARRHYTHMIA AGENTS, AMINOPIPERIDINE DERIVATIVES BEECHAM WUELFING GMBH & CO. KG (DE) 1986-07-29 US disclosed
US-4453252-A A PYRAZOLOAZAXANTHENOISOQUINOLINONE DYE MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1984-06-05 US disclosed
US-4444768-A ICE CREAM CONE WRAPPER CIBA-GEIGY CORPORATION (US) 1984-04-24 US disclosed
EP-0097000-A2 Amine derivatives Beecham Wuelfing GmbH &amp; Co KG (DE) 1983-12-28 EP disclosed
US-4415494-A BLUE-TO-BLACK COLORFAST DISPERSE, NITRO DYES; DIAZOTIZING A P-NITROANILINE AND COUPLING WITH AN N-SUBSTITUTED 1-NAPHTHYLAMINE CASSELLA AKTIENGESELLSCHAFT (DE) 1983-11-15 US disclosed
US-4296128-A ANTITHROMBOSIS AGENTS CIBA-GEIGY CORPORATION (US) 1981-10-20 US disclosed
EP-0036545-A1 Water insoluble monoazo dyes, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1981-09-30 EP disclosed