Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 15/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22173731 | 0.84 | HDAC6 (0.42) | HDAC6BCHEACHEMEN1KMT2A | |
| SCHEMBL29851224 | 0.82 | HDAC6 (0.62) | HDAC6BCHEACHEMAOANOX1 | |
| SCHEMBL12190901 | 0.82 | HDAC6 (0.62) | HDAC6BCHEACHEMAOANOX1 | |
| SCHEMBL30436360 | 0.80 | HDAC6 (0.54) | HDAC6BCHEACHEMAOANOX1 | |
| SCHEMBL4243905 | 0.80 | HDAC6 (0.54) | HDAC6BCHEACHEMAOANOX1 | |
| SCHEMBL19367113 | 0.80 | HDAC6 (0.41) | HDAC6BCHEACHEMAOANOX1 | |
| SCHEMBL15470447 | 0.80 | HDAC6 (0.57) | HDAC6BCHEACHEMAOANOX1 | |
| SCHEMBL342426 | 0.80 | HDAC6 (0.56) | HDAC6BCHEACHEMAOANOX1 | |
| SCHEMBL29387100 | 0.80 | HDAC6 (0.56) | HDAC6BCHEACHEMAOANOX1 | |
| SCHEMBL21510255 | 0.79 | HDAC6 (0.38) | HDAC6BCHEACHEMAOANOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984079-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | Power Oleds Limited (GB) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014167286-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LIMITED (GB) | 2014-10-16 | — | — | WO | disclosed |