SCHEMBL15470447

SCHEMBL15470447

c1ccc2c(c1)Sc1ccccc1N2c1ccc(-c2ccc(N3c4ccccc4Sc4ccccc43)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.57
MAOA P21397 1/20 0.50
BCHE P06276 8/20 0.45
ACHE P22303 3/20 0.42
NOX1 Q9Y5S8 2/20 0.42
FAAH O00519 1/20 0.41
MGLL Q99685 1/20 0.41
PTGS1 P23219 2/20 0.39
PTGS2 P35354 2/20 0.39
KDM1A O60341 1/20 0.39
PIM1 P11309 1/20 0.39
MEN1 O00255 1/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
CHRM3 P20309 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2C P28335 1/20 0.38
SLC6A4 P31645 1/20 0.38
DRD3 P35462 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4243905 0.96 HDAC6 (0.54) HDAC6MAOABCHEACHENOX1
SCHEMBL30436360 0.96 HDAC6 (0.54) HDAC6MAOABCHEACHENOX1
SCHEMBL12190901 0.93 HDAC6 (0.62) HDAC6MAOABCHEACHENOX1
SCHEMBL29851224 0.93 HDAC6 (0.62) HDAC6MAOABCHEACHENOX1
SCHEMBL23555415 0.91 HDAC6 (0.50) HDAC6MAOABCHENOX1PTGS1
SCHEMBL23057479 0.91 HDAC6 (0.54) HDAC6MAOABCHEACHENOX1
SCHEMBL19270161 0.89 HDAC6 (0.49) HDAC6MAOABCHEACHENOX1
SCHEMBL16449658 0.87 HDAC6 (0.54) HDAC6MAOABCHEACHENOX1
SCHEMBL342426 0.86 HDAC6 (0.56) HDAC6MAOABCHEACHENOX1
SCHEMBL29387100 0.86 HDAC6 (0.56) HDAC6MAOABCHEACHENOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190305228-A1 ORGANIC LIGHTEMITTING COMPOUND HAVING PHOSPHORESCENT CHARACTERISTIC AT ROOM TEMPERATURE, AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DEVICE INCLUDING THE ORGANIC LIGHTEMITTING COMPOUND RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVER SITY (KR) 2019-10-03 US disclosed
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190305228-A1 ORGANIC LIGHTEMITTING COMPOUND HAVING PHOSPHORESCENT CHARACTERISTIC AT ROOM TEMPERATURE, AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DEVICE INCLUDING THE ORGANIC LIGHTEMITTING COMPOUND MAP1LC3C, MAP1LC3A, MAP1LC3B HDAC6 4794/4885MAOA 2358/4885BCHE 4076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.