Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | F13A1 | P00488 | 3/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | MC5R | P33032 | 1/20 | 0.49 |
| ▸ | MC3R | P41968 | 1/20 | 0.49 |
| ▸ | MC1R | Q01726 | 1/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842066 | 1.00 | TDP1 (0.59) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL29865501 | 1.00 | TDP1 (0.59) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL29865603 | 1.00 | TDP1 (0.59) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL11414169 | 1.00 | TDP1 (0.59) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL3732554 | 1.00 | TDP1 (0.59) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL710750 | 1.00 | TDP1 (0.59) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6472349 | 0.98 | TDP1 (0.57) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL27632418 | 0.98 | TDP1 (0.57) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6472220 | 0.98 | TDP1 (0.57) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL22129565 | 0.98 | TDP1 (0.61) | TDP1MEN1KMT2AMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404460-B2 | Method for detecting and/or identifying Clostridium difficile | BIOMERIEUX (FR) | 2013-03-26 | — | — | US | disclosed |
| US-7923211-B2 | Method of calibrating ligand specificity | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2011-04-12 | — | — | US | disclosed |
| US-20100279330-A1 | METHOD FOR DETECTING AND/OR IDENTIFYING CLOSTRIDIUM DIFFICILE | BIOMERIEUX (FR) | 2010-11-04 | — | — | US | disclosed |
| US-20090305435-A1 | METHOD OF CALIBRATING LIGAND SPECIFICITY | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-7592187-B2 | Method of calibrating ligand specificity | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2009-09-22 | — | — | US | disclosed |
| US-20070122913-A1 | Method of calibrating ligand specificity | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2007-05-31 | — | — | US | disclosed |
| US-RE36385-E | TREATMENT OF TUMORS, ENHANCING IMMUNITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0226381-B1 | NOVEL GLUCOPYRANOSE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-4925929-A | ANTITUMOR AGENTS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0226381-A2 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-06-24 | — | — | EP | disclosed |