Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | F13A1 | P00488 | 3/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | MC5R | P33032 | 1/20 | 0.49 |
| ▸ | MC3R | P41968 | 1/20 | 0.49 |
| ▸ | MC1R | Q01726 | 1/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842066 | 1.00 | TDP1 (0.59) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL29865501 | 1.00 | TDP1 (0.59) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL29865603 | 1.00 | TDP1 (0.59) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL11414169 | 1.00 | TDP1 (0.59) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL1616841 | 1.00 | TDP1 (0.59) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL3732554 | 1.00 | TDP1 (0.59) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6472349 | 0.98 | TDP1 (0.57) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL27632418 | 0.98 | TDP1 (0.57) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6472220 | 0.98 | TDP1 (0.57) | TDP1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL22129565 | 0.98 | TDP1 (0.61) | TDP1MEN1KMT2AMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033067-A1 | SALT OF 1,2,6,7,8,8A-HEXAHYDRO-β,δ,6-TRIHYDROXY-2-METHYL-8-[(2S)-2-METHYL-1-OXOBUTOXY]-, (βR,δ R,1S,2S,6S,8S,8AR)- 1-NAPHTHALENEHEPTANOIC ACID WITH N,N-DIMETHYL-IMIDODICARBONIMIDIC DIAMIDE | BIOCON LIMITED (IN) | 2005-04-14 | — | — | WO | claimed |
| WO-2005019155-A1 | PROCESS FOR THE PREPARATION OF 1,2,6,7,8,8A-HEXAHYDRO-BETA,DELTA,6-TRIHYDROXY-2-METHYL-8-[(2S)-2-METHYL-1-OXOBUTOXY]-, (BETA R,DELTA R,1S,2S,6S,8S,8AR)-1-NAPHTHALENEHEPTANOIC ACID, SODIUM SALT. | BIOCON LIMITED (IN) | 2005-03-03 | — | — | WO | claimed |
| US-11897918-B2 | Compositions and methods to increase production | Seqirus UK Limited (GB) | 2024-02-13 | — | — | US | disclosed |
| CN-106471119-B | Compositions and methods for increasing yield | 思齐乐 | 2020-11-10 | — | — | CN | disclosed |
| EP-3131578-B1 | COMPOSITIONS AND METHODS TO INCREASE PRODUCTION | SEQIRUS UK LTD (GB) | 2020-06-03 | — | — | EP | disclosed |
| US-20200040040-A1 | COMPOSITIONS AND METHODS TO INCREASE PRODUCTION | NOVARTIS (CH) | 2020-02-06 | — | — | US | disclosed |
| US-20190106592-A1 | HYPERBRANCHED POLYMERS FOR ORGANIC PIGMENT DISPERSIONS AND WATER-SENSITIVE PIGMENTS | BASF COATINGS GMBH (DE) | 2019-04-11 | — | — | US | disclosed |
| CN-106471119-A | Compositions and methods for increasing yield | 诺华股份有限公司 | 2017-03-01 | — | — | CN | disclosed |
| EP-3131578-A1 | COMPOSITIONS AND METHODS TO INCREASE PRODUCTION | Novartis AG (CH) | 2017-02-22 | — | — | EP | disclosed |
| US-20170044216-A1 | COMPOSITIONS AND METHODS TO INCREASE PRODUCTION | Seqirus UK Limited (GB) | 2017-02-16 | — | — | US | disclosed |
| US-9353218-B2 | Kit for multifunctional compounds forming crosslinked biomaterials | ANGIOTECH PHARMACEUTICALS, INC. | 2016-05-31 | — | — | US | disclosed |
| WO-2002096347-A2 | METERING AND PACKAGING OF CONTROLLED RELEASE MEDICATION | MICRODOSE TECHNOLOGIES, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
| WO-2002087556-A2 | PROBUCOL MONOESTERS AND THEIR USE TO INCREASE PLASMA HDL CHOLESTEROL LEVELS AND IMPROVE HDL FUNCTIONALITY | ATHEROGENICS, INC. (US) | 2002-11-07 | — | — | WO | disclosed |
| US-6441029-B1 | D-.GAMMA.-TOCOTRIENOL, 2-DESMETHYLTOCOTRIENOL, D-.DELTA.-TOCOTRIENOL OR D-TOCOTRIENOL AND LOVASTATIN | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2002-08-27 | — | — | US | disclosed |
| US-20020016364-A1 | Compounds and methods to increase plasma HDL cholesterol levels and improve HDL functionality | CRABTREE ACQUISITION CO, LLC | 2002-02-07 | — | — | US | disclosed |
| US-20020004521-A1 | Use of HMG-COA reductase inhibitors to prevent and treat BPH | WEISMAN KENNETH (US) | 2002-01-10 | — | — | US | disclosed |
| WO-2001077072-A2 | COMPOUNDS AND METHODS TO INCREASE PLASMA HDL CHOLESTEROL LEVELS AND IMPROVE HDL FUNCTIONALITY | ATHEROGENICS, INC. (US) | 2001-10-18 | — | — | WO | disclosed |
| US-6133312-A | ORALLY ADMINISTERING A SYNERGISTIC TOCOTRIENOL AND IONONE MIXTURE TO INHIBIT TUMOR GROWTH | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2000-10-17 | — | — | US | disclosed |
| EP-0986383-A1 | METHOD OF SUPPRESSING TUMOR GROWTH WITH COMBINATIONS OF ISOPRENOIDS AND STATINS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998038993-A1 | METHOD OF SUPPRESSING TUMOR GROWTH WITH COMBINATIONS OF ISOPRENOIDS AND STATINS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1998-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190106592-A1 | HYPERBRANCHED POLYMERS FOR ORGANIC PIGMENT DISPERSIONS AND WATER-SENSITIVE PIGMENTS | TYR, PAH, AHR | TDP1 888/4885MEN1 2875/4885KMT2A 970/4885 |
| US-20170044216-A1 | COMPOSITIONS AND METHODS TO INCREASE PRODUCTION | MRPL21, CHLSN, MAX | TDP1 3386/4885MEN1 3222/4885KMT2A 4670/4885 |
| US-20200040040-A1 | COMPOSITIONS AND METHODS TO INCREASE PRODUCTION | MRPL21, CHLSN, MAX | TDP1 3386/4885MEN1 3222/4885KMT2A 4670/4885 |
| US-11897918-B2 | Compositions and methods to increase production | MRPL21, CHLSN, MAX | TDP1 3386/4885MEN1 3222/4885KMT2A 4670/4885 |
| US-20020016364-A1 | Compounds and methods to increase plasma HDL cholesterol levels and improve HDL functionality | HDLBP, CETP, APOB | TDP1 2635/4885MEN1 3946/4885KMT2A 4351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.