SCHEMBL16168528

SCHEMBL16168528

O=C1c2ccccc2C2C=CC=CC12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
POLB P06746 2/20 0.43
S100A4 P26447 2/20 0.38
CYP2D6 P10635 1/20 0.36
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.35
MAPK1 P28482 2/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
HTR2B P41595 1/20 0.35
CDC25B P30305 1/20 0.35
PIM1 P11309 1/20 0.34
ALDH1A1 P00352 1/20 0.34
SCN1A P35498 1/20 0.34
SCN2A Q99250 1/20 0.34
SCN3A Q9NY46 1/20 0.34
PBRM1 Q86U86 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29689764 0.86 KMT2A (0.50) MEN1KMT2APOLBS100A4LMNA
SCHEMBL278741 0.86 KMT2A (0.50) MEN1KMT2APOLBS100A4LMNA
SCHEMBL19456485 0.77 CYP2D6 (0.44) MEN1KMT2APOLBS100A4CYP2D6
SCHEMBL24123358 0.76 GSTP1 (0.33) MEN1KMT2APOLBLMNAMAPK1
SCHEMBL17792652 0.75 MEN1 (0.32) MEN1KMT2AMAPTTP53CYP3A4
SCHEMBL12070597 0.75 USP8 (0.41) MEN1KMT2APOLBS100A4CYP2D6
SCHEMBL11966872 0.74 GSTP1 (0.38) MEN1KMT2APOLBS100A4LMNA
SCHEMBL12343883 0.74 SCN1A (0.34) SCN1ASCN2ASCN3A
SCHEMBL24277966 0.74 EDNRB (0.39) MEN1KMT2APOLBLMNACYP1A2
SCHEMBL13645244 0.74 MEN1 (0.35) MEN1KMT2APOLBS100A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4215576-A1 COMPOSITION FOR FLUORINE RUBBER CROSSLINKING AND MOLDED ARTICLE Daikin Industries, Ltd. (JP) 2023-07-26 EP disclosed
US-9206287-B2 Fluorene derivatives and lens using the same SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2015-12-08 US disclosed
US-9206287-B2 Fluorene derivatives and lens using the same SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2015-12-08 US disclosed
US-20150025215-A1 Fluorene derivatives and lens using the same SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2015-01-22 US disclosed
US-20150025215-A1 Fluorene derivatives and lens using the same SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2015-01-22 US disclosed
EP-2154105-B1 More advanced preparation method of organic-transition metal hydride complexes containing aryl group or alkyl group as hydrogen storage materials HANWHA CHEMICAL CORP (KR) 2014-10-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150025215-A1 Fluorene derivatives and lens using the same UACA, AFF1, AFF2 MEN1 506/4885KMT2A 2236/4885POLB 4520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.