Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.33 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375191 | 0.89 | CHRNA7 (0.39) | CHRNA7SIGMAR1GBA1TP53HIF1A | |
| SCHEMBL1964501 | 0.82 | CHRNA7 (0.44) | CHRNA7TP53HIF1ACYP2D6CHRNB4 | |
| SCHEMBL8965143 | 0.81 | CHRNA7 (0.43) | CHRNA7TP53HIF1ACYP2D6CHRNB4 | |
| SCHEMBL5944660 | 0.81 | CHRNA7 (0.43) | CHRNA7TP53HIF1ACYP2D6CHRNB4 | |
| SCHEMBL7782665 | 0.81 | SIGMAR1 (0.37) | SIGMAR1GBA1HIF1ACYP2D6SLC6A2 | |
| SCHEMBL10860816 | 0.79 | SIGMAR1 (0.37) | SIGMAR1GBA1HIF1ACYP2D6SLC6A2 | |
| SCHEMBL8056810 | 0.78 | CHRNA7 (0.44) | CHRNA7SIGMAR1TP53HIF1ACYP2D6 | |
| SCHEMBL7833641 | 0.77 | CHRM3 (0.43) | CHRNA7SIGMAR1GBA1HIF1AKMT2A | |
| SCHEMBL15624979 | 0.75 | CHRNA7 (0.39) | CHRNA7TP53HIF1ACYP2D6KMT2A | |
| SCHEMBL6440687 | 0.75 | HIF1A (0.47) | SIGMAR1GBA1HIF1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2644379-B1 | Method of producing a planographic printing plate | FUJIFILM CORP (JP) | 2014-10-15 | — | — | EP | disclosed |