Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 8/20 | 0.41 |
| ▸ | FER | P16591 | 6/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | CAMK1D | Q8IU85 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10254793 | 0.88 | FER (0.47) | SYKFERHDAC4HDAC6AAK1 | |
| SCHEMBL16169195 | 0.88 | SYK (0.46) | SYKFERHDAC4HDAC6AAK1 | |
| SCHEMBL16165590 | 0.87 | FER (0.44) | SYKFERCAMK1DKDM4EMAPT | |
| SCHEMBL16169199 | 0.87 | SYK (0.48) | SYKFERHDAC4HDAC6AAK1 | |
| SCHEMBL16169186 | 0.87 | FER (0.47) | SYKFERHDAC4HDAC6AAK1 | |
| SCHEMBL14911009 | 0.85 | FER (0.46) | SYKFERHDAC4HDAC6AAK1 | |
| SCHEMBL14929401 | 0.85 | FER (0.46) | SYKFERHDAC4HDAC6AAK1 | |
| SCHEMBL16169190 | 0.85 | FER (0.49) | SYKFERAAK1KDM4E | |
| SCHEMBL16169188 | 0.85 | FER (0.46) | SYKFERHDAC4HDAC6AAK1 | |
| SCHEMBL14911011 | 0.85 | FER (0.46) | SYKFERHDAC4HDAC6AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051310-B2 | Nicotinamide derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2015-06-09 | — | — | US | disclosed |
| US-20140309225-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2014-10-16 | — | — | US | disclosed |
| US-20140309225-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2014-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309225-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | SYK, BTK, NOX4 | SYK 1/4885FER 441/4885HDAC4 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.