Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 18/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | FER | P16591 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19790653 | 0.91 | SYK (0.66) | SYKKCNH2FER | |
| SCHEMBL16165491 | 0.89 | SYK (0.62) | SYKKCNH2FER | |
| SCHEMBL16169366 | 0.88 | SYK (0.58) | SYKKCNH2 | |
| SCHEMBL16169189 | 0.88 | SYK (0.46) | SYKFER | |
| SCHEMBL9107832 | 0.86 | SYK (0.74) | SYKKCNH2FER | |
| SCHEMBL14911394 | 0.86 | SYK (0.74) | SYKKCNH2FER | |
| SCHEMBL14910430 | 0.86 | SYK (0.74) | SYKKCNH2FER | |
| SCHEMBL16169271 | 0.85 | SYK (0.56) | SYK | |
| SCHEMBL16169369 | 0.85 | SYK (0.58) | SYKFER | |
| SCHEMBL16169363 | 0.85 | FER (0.60) | SYKKCNH2FER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140309225-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2014-10-16 | — | — | US | disclosed |
| US-20140309225-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2014-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309225-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | SYK, BTK, NOX4 | SYK 1/4885KCNH2 1953/4885FER 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.