SCHEMBL1617434

SCHEMBL1617434

S=C1C=[C]N=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6399151 0.59
SCHEMBL121683 0.54
SCHEMBL235473 0.49
SCHEMBL451356 0.46
SCHEMBL4362773 0.41
SCHEMBL193794 0.41
SCHEMBL18032665 0.40
SCHEMBL329489 0.38
SCHEMBL380648 0.32
SCHEMBL9559497 0.32

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100129794-A1 Magnetic Polymer Particles QIAGEN GMBH (DE) 2010-05-27 US claimed
EP-1963413-A1 MAGNETIC POLYMER PARTICLES Qiagen GmbH (DE) 2008-09-03 EP claimed
WO-2007065933-A1 MAGNETIC POLYMER PARTICLES QIAGEN GMBH (DE) 2007-06-14 WO claimed
US-7115632-B1 Sulfonyl aryl or heteroaryl hydroxamic acid compounds G. D. SEARLE & CO. (US) 2006-10-03 US claimed
US-6890937-B2 Aromatic sulfone hydroxamic acid metalloprotease inhibitor PHARMACIA CORPORATION (US) 2005-05-10 US claimed
US-6750233-B2 SELECTIVITY PHARMACIA CORPORATION 2004-06-15 US claimed
US-20040097487-A1 Aromatic sulfonyl alpha-cycloamino hydroxamic acid compounds G.D. SEARLE & CO. 2004-05-20 US claimed
US-20040048852-A1 Aromatic sulfone hydroxamic acid metalloprotease inhibitor PHARMACIA CORPORATION 2004-03-11 US claimed
US-6656954-B2 Such as N-hydroxy-2-(((4-phenoxyphenyl)-sulfonyl)methyl) benzamide which inhibits matrix metalloprotease activity PHARMACIA CORPORATION 2003-12-02 US claimed
EP-0973392-B1 SULFONYL DIVALENT ARYL OR HETEROARYL HYDROXAMIC ACID COMPOUNDS MONSANTO CO (US) 2003-11-19 EP claimed
EP-0973392-A1 SULFONYL DIVALENT ARYL OR HETEROARYL HYDROXAMIC ACID COMPOUNDS MONSANTO COMPANY (US) 2000-01-26 EP claimed
US-6013649-A BOND DISORDERS; AUTOIMMUNE DISEASES; ANTITUMOR AGENTS MONSANTO COMPANY (US) 2000-01-11 US claimed
EP-0939628-A4 THIOL SULFONE METALLOPROTEASE INHIBITORS MONSANTO CO (US) 1999-12-22 EP claimed
EP-0939628-A1 THIOL SULFONE METALLOPROTEASE INHIBITORS MONSANTO COMPANY (US) 1999-09-08 EP claimed
WO-1999025687-A1 AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR G.D. SEARLE & CO. (US) 1999-05-27 WO claimed
WO-1998039316-A1 N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS MONSANTO COMPANY (US) 1998-09-11 WO claimed
WO-1998038859-A1 SULFONYL DIVALENT ARYL OR HETEROARYL HYDROXAMIC ACID COMPOUNDS MONSANTO COMPANY (US) 1998-09-11 WO claimed
WO-1998039315-A1 AROMATIC SULFONYL ALPHA-CYCLOAMINO HYDROXAMIC ACID COMPOUNDS MONSANTO COMPANY (US) 1998-09-11 WO claimed
WO-1998039326-A1 AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS MONSANTO COMPANY (US) 1998-09-11 WO claimed
WO-1998003164-A1 THIOL SULFONE METALLOPROTEASE INHIBITORS MONSANTO COMPANY (US) 1998-01-29 WO claimed