⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046450 | 0.92 | — | — | |
| SCHEMBL541637 | 0.86 | TSHR (0.61) | — | |
| SCHEMBL12532716 | 0.83 | — | — | |
| SCHEMBL21831585 | 0.83 | TSHR (0.58) | — | |
| SCHEMBL26245 | 0.83 | LMNA (0.53) | — | |
| SCHEMBL542077 | 0.83 | TSHR (0.58) | — | |
| SCHEMBL29629355 | 0.83 | TSHR (0.58) | — | |
| SCHEMBL21409909 | 0.83 | TSHR (0.58) | — | |
| SCHEMBL22129601 | 0.83 | TSHR (0.58) | — | |
| SCHEMBL9618070 | 0.83 | TSHR (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118127663-B | Method for preparing flame-retardant DTY polyester yarns by regenerating polyester fibers | 安徽保尔盈新材料科技有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-118127663-A | Method for preparing flame-retardant DTY polyester yarns by regenerating polyester fibers | 安徽保尔盈新材料科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| EP-3571208-B1 | IMMUNOPROTEASOME INHIBITORS | PRINCIPIA BIOPHARMA INC (US) | 2021-03-10 | — | — | EP | disclosed |
| WO-2018136401-A1 | IMMUNOPROTEASOME INHIBITORS | PRINCIPIA BIOPHARMA INC. (US) | 2018-07-26 | — | — | WO | disclosed |
| US-9428448-B2 | Compounds and methods of treating obesity | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2016-08-30 | — | — | US | disclosed |
| US-20140309273-A1 | COMPOUNDS AND METHODS OF TREATING OBESITY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2014-10-16 | — | — | US | disclosed |