(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL16174458

C(=C/c1ccccc1)\c1ccccc1.c1ccc2cc3ccccc3cc2c1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.73
MAOB P27338 3/20 0.55
PDGFRB P09619 1/20 0.54
PDGFRA P16234 1/20 0.54
NFE2L2 Q16236 2/20 0.52
CYP19A1 P11511 2/20 0.52
MAOA P21397 2/20 0.52
TRPA1 O75762 1/20 0.52
KDM4E B2RXH2 3/20 0.52
ALDH1A1 P00352 2/20 0.52
HPGD P15428 2/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
NPC1 O15118 1/20 0.50
LMNA P02545 1/20 0.50
PKM P14618 1/20 0.50
RAB9A P51151 1/20 0.50
CYP1B1 Q16678 1/20 0.48
TTR P02766 1/20 0.48
ALOX5 P09917 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL16161956 1.00 RELA (0.73) RELAMAOBPDGFRBPDGFRANFE2L2
Anthracene SCHEMBL7792267 0.89 MAOB (0.74) RELAMAOBPDGFRBPDGFRANFE2L2
Anthracene SCHEMBL2035098 0.89 MAOB (0.74) RELAMAOBPDGFRBPDGFRANFE2L2
SCHEMBL5406013 0.88 RELA (0.87) RELAMAOBPDGFRBPDGFRANFE2L2
SCHEMBL5406009 0.88 RELA (0.87) RELAMAOBPDGFRBPDGFRANFE2L2
SCHEMBL5406016 0.88 RELA (0.87) RELAMAOBPDGFRBPDGFRANFE2L2
SCHEMBL10665971 0.87 RELA (0.64) RELAMAOBPDGFRBPDGFRANFE2L2
SCHEMBL10665973 0.87 RELA (0.64) RELAMAOBPDGFRBPDGFRANFE2L2
SCHEMBL5407848 0.85 RELA (1.00) RELAPDGFRBPDGFRANFE2L2KDM4E
SCHEMBL5548861 0.85 RELA (0.83) RELAMAOBPDGFRBPDGFRANFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8866100-B1 Time encoded radiation imaging SANDIA CORPORATION (US) 2014-10-21 US disclosed