Propene

Propene

SCHEMBL1617448

C=CC.CC1=CC(=O)CC(C)(C)C1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 1/20 0.43
MAPT P10636 4/20 0.42
HPGD P15428 2/20 0.42
LMNA P02545 2/20 0.40
TSHR P16473 2/20 0.38
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
GLA P06280 1/20 0.37
ALOX15 P16050 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
NCOA1 Q15788 1/20 0.37
NCOA3 Q9Y6Q9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL9579550 0.98 ALDH1A1 (0.43) ALDH1A1KMT2AMEN1NPC1RAB9A
SCHEMBL7102666 0.89 ALDH1A1 (0.52) ALDH1A1KMT2AMEN1NPC1RAB9A
SCHEMBL22522 0.89 ALDH1A1 (0.52) ALDH1A1KMT2AMEN1NPC1RAB9A
SCHEMBL271129 0.87 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1NPC1RAB9A
Ammonia Solution, Strong SCHEMBL1984334 0.87 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1NPC1RAB9A
Water SCHEMBL9637163 0.87 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1NPC1RAB9A
Ammonia Solution, Strong SCHEMBL7735826 0.87 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1NPC1RAB9A
Ammonia Solution, Strong SCHEMBL10613596 0.87 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1NPC1RAB9A
SCHEMBL11132973 0.87 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1NPC1RAB9A
Water SCHEMBL28863261 0.87 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963392-B2 MULTILAYER COATING SYSTEM AKZO NOBEL COATINGS INT BV (NL) 2012-08-01 EP disclosed
US-7923113-B2 Shorter drying times; clear coats; addition of a basic catalyst; isocyanate-functional compound and thiol-functional compound; useful in repair and refinish of automobiles AKZO NOBEL COATING INTERNATIONAL B.V. (NL) 2011-04-12 US disclosed
EP-1963392-B1 MULTILAYER COATING SYSTEM AKZO NOBEL COATINGS INT BV (NL) 2009-08-05 EP disclosed
US-20090142600-A1 MULTILAYER COATING SYSTEM AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2009-06-04 US disclosed
EP-1242548-B2 AQUEOUS COATING COMPOSITION COMPRISING AN ADDITION POLYMER AND A POLYURETHANE AKZO NOBEL COATINGS INT BV (NL) 2009-02-25 EP disclosed
EP-1963392-A1 MULTILAYER COATING SYSTEM Akzo Nobel Coatings International BV (NL) 2008-09-03 EP disclosed
WO-2007068683-A1 MULTILAYER COATING SYSTEM AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2007-06-21 WO disclosed
EP-1242548-B1 AQUEOUS COATING COMPOSITION COMPRISING AN ADDITION POLYMER AND A POLYURETHANE AKZO NOBEL COATINGS INT BV (NL) 2005-06-15 EP disclosed
US-6552117-B2 Alkali-swellable core-shell addition polymer andpolyurethane used as base coat; good mechanical properties, high flop, high gloss, no strike-in, good water-resistance, efficiency AKZO NOBEL N.V. (NL) 2003-04-22 US disclosed
EP-1242548-A1 AQUEOUS COATING COMPOSITION COMPRISING AN ADDITION POLYMER AND A POLYURETHANE Akzo Nobel N.V. (NL) 2002-09-25 EP disclosed
US-20010023273-A1 Aqueous coating composition comprising an addition polymer and a polyurethane AKZO NOBEL N.V. (NL) 2001-09-20 US disclosed
WO-2001048106-A1 AQUEOUS COATING COMPOSITION COMPRISING AN ADDITION POLYMER AND A POLYURETHANE AKZO NOBEL N.V. (NL) 2001-07-05 WO disclosed
US-5141987-A Waterbase paints has aluminum pigment and anionic polymers containing carbonate urethane and urea groupd; waterproofing; automobiles BAYER AKTIENGESELLSCHAFT (DE) 1992-08-25 US disclosed
US-4764553-A Water soluble or dispersible polyurethanes, a process for their preparation and their use for coating substrates BAYER AKTIENGESELLSCHAFT (DE) 1988-08-16 US disclosed