Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 16/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16175168 | 0.86 | SCN9A (0.45) | SCN9ASCN5AACACB | |
| SCHEMBL365992 | 0.85 | SCN9A (0.46) | SCN9ASCN5AACACB | |
| SCHEMBL16175392 | 0.84 | SCN9A (0.60) | SCN9ASCN5A | |
| SCHEMBL19411389 | 0.84 | SCN9A (0.56) | SCN9ASCN5A | |
| SCHEMBL365758 | 0.84 | SCN9A (0.55) | SCN9ASCN5A | |
| SCHEMBL15543345 | 0.81 | SCN9A (0.53) | SCN9ASCN5A | |
| SCHEMBL365032 | 0.81 | SCN9A (0.46) | SCN9ASCN5AACACBS1PR1 | |
| SCHEMBL365976 | 0.79 | SCN9A (0.46) | SCN9ASCN5AACACB | |
| SCHEMBL15543581 | 0.79 | SCN9A (0.68) | SCN9ASCN5A | |
| SCHEMBL16175242 | 0.79 | SCN9A (0.49) | SCN9ASCN5AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593432-B1 | N-SULFONYLBENZAMIDE DERIVATIVES USEFUL AS VOLTAGE GATED SODIUM CHANNEL INHIBITORS | PFIZER LTD (GB) | 2014-10-22 | — | — | EP | disclosed |