Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3986691 | 0.94 | METAP2 (1.00) | METAP2 | |
| SCHEMBL3988213 | 0.94 | METAP2 (1.00) | METAP2 | |
| SCHEMBL3986694 | 0.94 | METAP2 (1.00) | METAP2 | |
| SCHEMBL12037940 | 0.91 | METAP2 (0.84) | METAP2 | |
| SCHEMBL21017472 | 0.90 | METAP2 (0.83) | METAP2 | |
| SCHEMBL3979227 | 0.90 | METAP2 (1.00) | METAP2 | |
| SCHEMBL3982013 | 0.90 | METAP2 (1.00) | METAP2 | |
| SCHEMBL3979223 | 0.90 | METAP2 (1.00) | METAP2 | |
| SCHEMBL12022091 | 0.89 | METAP2 (0.81) | METAP2 | |
| SCHEMBL19880254 | 0.89 | METAP2 (0.81) | METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014169026-A1 | METAP2 INHIBITORS AND METHODS OF TREATING OBESITY | SYNDEVRX, INC. (US) | 2014-10-16 | — | — | WO | disclosed |