Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 6/20 | 0.47 |
| ▸ | JAK2 | O60674 | 5/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21598927 | 1.00 | POLB (0.50) | POLBUSP30TRPV1JAK3JAK2 | |
| SCHEMBL16177330 | 1.00 | POLB (0.50) | POLBUSP30TRPV1JAK3JAK2 | |
| SCHEMBL24755093 | 0.94 | USP30 (0.55) | POLBUSP30JAK3JAK2BTK | |
| SCHEMBL28499786 | 0.94 | USP30 (0.55) | POLBUSP30JAK3JAK2BTK | |
| SCHEMBL27200991 | 0.94 | USP30 (0.55) | POLBUSP30JAK3JAK2BTK | |
| SCHEMBL30923690 | 0.94 | USP30 (0.55) | POLBUSP30JAK3JAK2BTK | |
| SCHEMBL16177033 | 0.88 | USP30 (0.50) | POLBUSP30TRPV1JAK3JAK2 | |
| SCHEMBL21598992 | 0.88 | USP30 (0.50) | POLBUSP30TRPV1JAK3JAK2 | |
| SCHEMBL16177034 | 0.88 | USP30 (0.50) | POLBUSP30TRPV1JAK3JAK2 | |
| SCHEMBL31227488 | 0.88 | USP30 (0.50) | POLBUSP30TRPV1JAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113387945-A | Compound PTM-3, PTM-4, preparation method and application of preparing medicine | 陈敏 | 2021-09-14 | — | — | CN | claimed |
| EP-4357345-A1 | CLY SERIES COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN PREPARATION OF DRUGS | Nanjing Wellbest Pharmaceutical Co., Ltd (CN) | 2024-04-24 | — | — | EP | disclosed |
| CN-113248501-B | CLY series compounds, preparation method thereof and application thereof in preparing medicines | 南京韦尔优众医药有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-113387945-A | Compound PTM-3, PTM-4, preparation method and application of preparing medicine | 陈敏 | 2021-09-14 | — | — | CN | disclosed |
| CN-113248501-A | CLY series compounds, preparation method thereof and application thereof in preparing medicines | 南京韦尔优众医药有限公司 | 2021-08-13 | — | — | CN | disclosed |
| WO-2016055901-A1 | SUBSTITUTED AMIDE COMPOUNDS | PFIZER INC. (US) | 2016-04-14 | — | — | WO | disclosed |
| US-20160102074-A1 | SUBSTITUTED AMIDE COMPOUNDS | PFIZER INC. (US) | 2016-04-14 | — | — | US | disclosed |
| US-20160058768-A1 | SUBSTITUTED AMIDE COMPOUNDS | PFIZER (US) | 2016-03-03 | — | — | US | disclosed |
| US-9227956-B2 | Substituted amide compounds | PFIZER INC. (US) | 2016-01-05 | — | — | US | disclosed |
| US-20140315928-A1 | SUBSTITUTED AMIDE COMPOUNDS | PFIZER INC. (US) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315928-A1 | SUBSTITUTED AMIDE COMPOUNDS | CETP, APOB, LCAT | POLB 3743/4885USP30 2477/4885TRPV1 3495/4885 |
| US-20160102074-A1 | SUBSTITUTED AMIDE COMPOUNDS | CETP, APOB, LCAT | POLB 3743/4885USP30 2477/4885TRPV1 3495/4885 |
| US-20160058768-A1 | SUBSTITUTED AMIDE COMPOUNDS | CETP, APOB, LCAT | POLB 3743/4885USP30 2477/4885TRPV1 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.