Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28130162 | 1.00 | HSD17B10 (0.48) | HSD17B10TAAR1CYP3A4TDP1ALDH1A1 | |
| SCHEMBL29638163 | 1.00 | HSD17B10 (0.48) | HSD17B10TAAR1CYP3A4TDP1ALDH1A1 | |
| SCHEMBL10608496 | 0.95 | HSD17B10 (0.48) | HSD17B10TAAR1CYP3A4TDP1ALDH1A1 | |
| SCHEMBL27952643 | 0.91 | HSD17B10 (0.56) | HSD17B10TAAR1CYP3A4TDP1ALDH1A1 | |
| SCHEMBL1838859 | 0.91 | HSD17B10 (0.48) | HSD17B10TAAR1CYP3A4TDP1ALDH1A1 | |
| SCHEMBL8573252 | 0.88 | ADORA2A (0.42) | HSD17B10TDP1ALDH1A1MAPTLMNA | |
| SCHEMBL28486075 | 0.87 | MAPT (0.47) | HSD17B10TAAR1CYP3A4TDP1ALDH1A1 | |
| SCHEMBL28070308 | 0.87 | ALDH1A1 (0.46) | HSD17B10TAAR1CYP3A4TDP1ALDH1A1 | |
| SCHEMBL9442622 | 0.86 | ALDH1A1 (0.50) | HSD17B10TAAR1CYP3A4TDP1ALDH1A1 | |
| SCHEMBL20657073 | 0.85 | HSD17B10 (0.57) | HSD17B10TAAR1CYP3A4TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10665787-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2020-05-26 | — | — | US | disclosed |
| US-10424739-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2019-09-24 | — | — | US | disclosed |
| US-20180269399-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-09-20 | — | — | US | disclosed |
| US-20180269398-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-09-20 | — | — | US | disclosed |
| US-10008672-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2018-06-26 | — | — | US | disclosed |
| US-20140312287-A1 | Compounds for Electronic Devices | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10008672-B2 | Compounds for electronic devices | KCNQ2, DDT, KCNQ1 | HSD17B10 3174/4885TAAR1 971/4885CYP3A4 312/4885 |
| US-20180269399-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | KCNQ2, DDT, KCNQ1 | HSD17B10 3174/4885TAAR1 971/4885CYP3A4 312/4885 |
| US-10424739-B2 | Compounds for electronic devices | KCNQ2, DDT, KCNQ1 | HSD17B10 3174/4885TAAR1 971/4885CYP3A4 312/4885 |
| US-10665787-B2 | Compounds for electronic devices | KCNQ2, DDT, KCNQ1 | HSD17B10 3174/4885TAAR1 971/4885CYP3A4 312/4885 |
| US-20180269398-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | KCNQ2, DDT, KCNQ1 | HSD17B10 3174/4885TAAR1 971/4885CYP3A4 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.