Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 15/20 | 0.73 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | HTR2B | P41595 | 1/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ib-Meca SCHEMBL29572081 | 0.81 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| Ib-Meca SCHEMBL8922766 | 0.81 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| Ib-Meca SCHEMBL29634441 | 0.81 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| Ib-Meca SCHEMBL10089200 | 0.81 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| Ib-Meca SCHEMBL10089244 | 0.81 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| Ib-Meca SCHEMBL465039 | 0.81 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| Ib-Meca SCHEMBL29384499 | 0.81 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| Ib-Meca SCHEMBL448115 | 0.81 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| Ib-Meca SCHEMBL20905217 | 0.81 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| Ib-Meca SCHEMBL12265127 | 0.81 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9301968-B2 | Therapeutic agent for inflammatory diseases, containing adenosine N1-oxide as an effective ingredient | Hayashibara Co., Ltd. (JP) | 2016-04-05 | — | — | US | disclosed |
| US-20140315849-A1 | THERAPEUTIC AGENT FOR INFLAMMATORY DISEASES, CONTAINING ADENOSINE N1-OXIDE AS AN EFFECTIVE INGREDIENT | Hayashibara Co., Ltd. (JP) | 2014-10-23 | — | — | US | disclosed |