Nitric Acid

Nitric Acid

SCHEMBL16178481

O.O.O.O.O.O.O=[N+]([O-])O.[Fe].[Fe]

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ERG11

The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.80
CA5B Q9Y2D0 1/20 0.80
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 3/20 0.33
TSHR P16473 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
HPGD P15428 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitric Acid SCHEMBL60725 1.00
Nitric Acid SCHEMBL27857239 1.00 CA5A (0.80) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL7672695 1.00 CA5A (0.80) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL7525228 1.00 CA5A (0.80) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL434245 1.00 CA5A (0.80) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL136878 1.00 CA5A (0.80) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL8170759 1.00 CA5A (0.80) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL28565841 0.95 CA5A (0.73) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL8170757 0.95 CA5A (0.73) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL28521504 0.95 CA5A (0.73) CA5ACA5BMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230150090-A1 METHODS OF FORMING A SUPERHARD STRUCTURE OR BODY COMPRISING A BODY OF POLYCHRYSTALLINE DIAMOND CONTAINING MATERIAL ELEMENT SIX ABRASIVES HOLDINGS LIMITED (GB) 2023-05-18 US disclosed
US-11529715-B2 Superhard structure or body comprising a body of polycrystalline diamond containing material ELEMENT SIX ABRASIVES S.A. (LU) 2022-12-20 US disclosed
US-20200047312-A1 SUPERHARD STRUCTURE OR BODY COMPRISING A BODY OF POLYCRYSTALLINE DIAMOND CONTAINING MATERIAL ELEMENT SIX ABRASIVES S.A. (LU) 2020-02-13 US disclosed
US-20190184525-A1 METHODS OF FORMING A SUPERHARD STRUCTURE OR BODY COMPRISING A BODY OF POLYCHRYSTALLINE DIAMOND CONTAINING MATERIAL ELEMENT SIX (PRODUCTION)(PTY) LTD (ZA) 2019-06-20 US disclosed
US-20170144271-A1 SUPERHARD STRUCTURE OR BODY COMPRISING A BODY OF POLYCRYSTALLINE DIAMOND CONTAINING MATERIAL ELEMENT SIX ABRASIVES S.A. (LU) 2017-05-25 US disclosed
US-20140345203-A1 SUPERHARD STRUCTURE OR BODY COMPRISING A BODY OF POLYCRYSTALLINE DIAMOND CONTAINING MATERIAL ELEMENT SIX ABRASIVES SA (LU) 2014-11-27 US disclosed
US-20140311045-A1 METHODS OF FORMING A SUPERHARD STRUCTURE OR BODY COMPRISING A BODY OF POLYCRYSTALLINE DIAMOND CONTAINING MATERIAL Element Six Abrasives S. A. (LU) 2014-10-23 US disclosed