SCHEMBL1617849

SCHEMBL1617849

Nc1cc(Br)nc(Br)c1N

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
BACE1 P56817 1/20 0.31
TERT O14746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13514619 0.79 BACE1 (0.35) GAAMAPTBACE1TERT
SCHEMBL21261372 0.75 TDP1 (0.40) HTR6TERT
SCHEMBL4596400 0.75 TDP1 (0.34) HTR6GAA
SCHEMBL31320527 0.75 NSD1 (0.33) HTR6
SCHEMBL30532685 0.75 HTR6 (0.31) HTR6
SCHEMBL27308732 0.75 KDM4E (0.31) HTR6
SCHEMBL10002681 0.75 GAA (0.32) HTR6GAA
SCHEMBL30432264 0.70 POLB (0.38) MAPT
SCHEMBL22684175 0.70 POLB (0.38) MAPT
SCHEMBL20075810 0.70 HTT (0.38) HTR6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7923529-B2 Oligothiophene-arylene derivatives and organic thin film transistors using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-04-12 US disclosed
US-20090256143-A1 OLIGOTHIOPHENE-ARYLENE DERIVATIVES AND ORGANIC THIN FILM TRANSISTORS USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-10-15 US disclosed
US-7541424-B2 Oligothiophene-arylene derivatives and organic thin film transistors using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-06-02 US disclosed
CN-1763035-A Oligothiophene-arylene derivatives and the OTFT of using it SAMSUNG ELECTRONICS CO LTD (KR) 2006-04-26 CN disclosed
US-20060081839-A1 Oligothiophene-arylene derivatives and organic thin film transistors using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-04-20 US disclosed