⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29725803 | 0.78 | — | — | |
| SCHEMBL4943693 | 0.78 | — | — | |
| SCHEMBL8586649 | 0.73 | — | — | |
| Bromide SCHEMBL2357681 | 0.73 | — | — | |
| Water SCHEMBL546028 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL545334 | 0.73 | — | — | |
| Iodide SCHEMBL2356598 | 0.73 | — | — | |
| Bromide SCHEMBL5190792 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL2357952 | 0.73 | — | — | |
| SCHEMBL2135832 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986239-A | Irbesartan preparation method | 珠海润都制药股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-20230119408-A1 | NUCLEOTIDE ANALOGS AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-04-20 | — | — | US | disclosed |
| US-7923566-B2 | Alternative process for the preparation of losartan | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-04-12 | — | — | US | disclosed |
| US-20100190996-A1 | Process for the Preparation of Losartan | SUVEN LIFE SCIENCES, LTD (IN) | 2010-07-29 | — | — | US | disclosed |
| WO-2007119246-A2 | AN IMPROVED PROCESS FOR THE MANUFACTURE OF LOSARTAN POTASSIUM | UNICHEM LABORATORIES LIMITED (IN) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007020654-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LOSARTAN | SUVEN LIFE SCIENCES (IN) | 2007-02-22 | — | — | WO | disclosed |
| EP-0578125-B1 | Tri-higher alkyl tin azide and its use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-04-01 | — | — | EP | disclosed |
| US-5484955-A | Tri-higher alkyl tin azide and its use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0578125-A1 | Tri-higher alkyl tin azide and its use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-01-12 | — | — | EP | disclosed |
| EP-0514192-A1 | Antihypertensive benzofuran derivatives, substituted by varied N-pyrimidinyl- or N-imidazolyl-methyl groups | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |
| WO-1992016552-A1 | 1-IMIDAZOLGEMETHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF ANGIOTENSIN II ACTIVITY | GLAXO GROUP LIMITED (GB) | 1992-10-01 | — | — | WO | disclosed |
| EP-0505954-A1 | N-Imidazolylmethyl benzofuran derivatives as inhibitors of angiotensin II activity | GLAXO GROUP LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |