Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2357681 | 1.00 | — | — | |
| SCHEMBL29725803 | 0.95 | — | — | |
| SCHEMBL4943693 | 0.95 | — | — | |
| SCHEMBL8586649 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL545334 | 0.90 | — | — | |
| Iodide SCHEMBL2356598 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL2357952 | 0.90 | — | — | |
| Water SCHEMBL546028 | 0.90 | — | — | |
| SCHEMBL1617902 | 0.73 | — | — | |
| Isothiocyanate SCHEMBL9446559 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461367-B1 | SYNTHESIS AND USE OF CHAIN-COUPLED POLYMERIC SULFIDE COMPOUNDS IN RUBBER FORMULATIONS | BRIDGESTONE CORP (JP) | 2007-06-27 | — | — | EP | claimed |
| EP-1280832-B1 | CHAIN-COUPLED POLYMERIC ALKOXIDE COMPOUNDS HAVING CONTROLLED VISCOSITY | BRIDGESTONE CORP (JP) | 2005-04-13 | — | — | EP | claimed |
| US-6806307-B2 | VULCANIZABLE ELASTOMERS; PNEUMATIC TIRES | BRIDGESTONE CORPORATION (JP) | 2004-10-19 | — | — | US | claimed |
| EP-1461367-A1 | SYNTHESIS AND USE OF CHAIN-COUPLED POLYMERIC SULFIDE COMPOUNDS IN RUBBER FORMULATIONS | Bridgestone Corporation (JP) | 2004-09-29 | — | — | EP | claimed |
| US-6573412-B1 | The elastomeric component in vulcanizable elastomeric compositions comprising silica, carbon black or mixtures. The invention provides anionically polymerized polymers having polymer chain living ends that are functionalize | BRIDGESTONE CORPORATION (JP) | 2003-06-03 | — | — | US | claimed |
| US-20030078335-A1 | Synthesis and use of chain-coupled polymeric sulfide compounds in rubber formulations | BRIDGESTONE CORPORATION | 2003-04-24 | — | — | US | claimed |
| WO-2003031484-A1 | SYNTHESIS AND USE OF CHAIN-COUPLED POLYMERIC SULFIDE COMPOUNDS IN RUBBER FORMULATIONS | BRIDGESTONE CORPORATION (JP) | 2003-04-17 | — | — | WO | claimed |
| EP-1280832-A2 | CHAIN-COUPLED POLYMERIC ALKOXIDE COMPOUNDS HAVING CONTROLLED VISCOSITY | Bridgestone Corporation (JP) | 2003-02-05 | — | — | EP | claimed |
| WO-2001087993-A2 | CHAIN-COUPLED POLYMERIC ALKOXIDE COMPOUNDS HAVING CONTROLLED VISCOSITY | BRIDGESTONE CORPORATION (JP) | 2001-11-22 | — | — | WO | claimed |
| EP-1461367-B1 | SYNTHESIS AND USE OF CHAIN-COUPLED POLYMERIC SULFIDE COMPOUNDS IN RUBBER FORMULATIONS | BRIDGESTONE CORP (JP) | 2007-06-27 | — | — | EP | disclosed |
| EP-1280832-B1 | CHAIN-COUPLED POLYMERIC ALKOXIDE COMPOUNDS HAVING CONTROLLED VISCOSITY | BRIDGESTONE CORP (JP) | 2005-04-13 | — | — | EP | disclosed |
| US-6806307-B2 | VULCANIZABLE ELASTOMERS; PNEUMATIC TIRES | BRIDGESTONE CORPORATION (JP) | 2004-10-19 | — | — | US | disclosed |
| EP-1461367-A1 | SYNTHESIS AND USE OF CHAIN-COUPLED POLYMERIC SULFIDE COMPOUNDS IN RUBBER FORMULATIONS | Bridgestone Corporation (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6573412-B1 | The elastomeric component in vulcanizable elastomeric compositions comprising silica, carbon black or mixtures. The invention provides anionically polymerized polymers having polymer chain living ends that are functionalize | BRIDGESTONE CORPORATION (JP) | 2003-06-03 | — | — | US | disclosed |
| US-20030078335-A1 | Synthesis and use of chain-coupled polymeric sulfide compounds in rubber formulations | BRIDGESTONE CORPORATION | 2003-04-24 | — | — | US | disclosed |
| WO-2003031484-A1 | SYNTHESIS AND USE OF CHAIN-COUPLED POLYMERIC SULFIDE COMPOUNDS IN RUBBER FORMULATIONS | BRIDGESTONE CORPORATION (JP) | 2003-04-17 | — | — | WO | disclosed |
| EP-1280832-A2 | CHAIN-COUPLED POLYMERIC ALKOXIDE COMPOUNDS HAVING CONTROLLED VISCOSITY | Bridgestone Corporation (JP) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001087993-A2 | CHAIN-COUPLED POLYMERIC ALKOXIDE COMPOUNDS HAVING CONTROLLED VISCOSITY | BRIDGESTONE CORPORATION (JP) | 2001-11-22 | — | — | WO | disclosed |