SCHEMBL1617973

SCHEMBL1617973

FC(F)(F)c1cc(-n2ccc3ccccc32)cc(C(F)(F)F)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BIRC5 O15392 1/20 0.54
KCNH2 Q12809 1/20 0.42
PRKD3 O94806 1/20 0.41
PRKCG P05129 1/20 0.41
PRKCB P05771 1/20 0.41
PRKCA P17252 1/20 0.41
PRKACA P17612 1/20 0.41
PRKACG P22612 1/20 0.41
PRKACB P22694 1/20 0.41
PRKCH P24723 1/20 0.41
PRKCI P41743 1/20 0.41
PRKCE Q02156 1/20 0.41
PRKCQ Q04759 1/20 0.41
PRKCZ Q05513 1/20 0.41
PRKCD Q05655 1/20 0.41
PRKD1 Q15139 1/20 0.41
GSR P00390 2/20 0.40
SLC6A4 P31645 2/20 0.40
HTR2A P28223 1/20 0.40
PLA2G10 O15496 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5663054 0.87 BIRC5 (0.51) BIRC5GSRSLC6A4HTR2APLA2G10
SCHEMBL29794926 0.87 BIRC5 (0.51) BIRC5GSRSLC6A4HTR2APLA2G10
SCHEMBL28220764 0.86 BIRC5 (0.62) BIRC5KCNH2PRKD3PRKCGPRKCB
SCHEMBL10153905 0.81 BIRC5 (0.64) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL2827266 0.79 BIRC5 (0.50) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL29475118 0.77 BIRC5 (0.70) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL170890 0.77 BIRC5 (0.70) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL6321704 0.77 BIRC5 (0.55) BIRC5KCNH2PRKD3PRKCGPRKCB
SCHEMBL5661431 0.76 CDC7 (0.54) BIRC5KCNH2PLA2G10KIF11RXFP1
Hydrochloric Acid SCHEMBL3803742 0.75 BIRC5 (0.68) BIRC5PRKD3PRKCGPRKCBPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7923091-B2 Indole compound, optical filter and optical recording material ADEKA CORPORATION (JP) 2011-04-12 US disclosed
EP-1921063-B1 INDOLE COMPOUND, OPTICAL FILTER AND OPTICAL RECORDING MATERIAL ADEKA CORP (JP) 2010-09-01 EP disclosed
US-20090092782-A1 INDOLE COMPOUND, OPTICAL FILTER AND OPTICAL RECORDING MATERIAL ADEKA CORPORATION (JP) 2009-04-09 US disclosed
EP-1921063-A1 INDOLE COMPOUND, OPTICAL FILTER AND OPTICAL RECORDING MATERIAL Adeka Corporation (JP) 2008-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090092782-A1 INDOLE COMPOUND, OPTICAL FILTER AND OPTICAL RECORDING MATERIAL HCRTR1, HCRTR2, KCNQ1 BIRC5 1768/4885KCNH2 17/4885PRKD3 3279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.