SCHEMBL170890

SCHEMBL170890

c1ccc(-n2ccc3ccccc32)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BIRC5 O15392 1/20 0.70
PRKD3 O94806 1/20 0.52
PRKCG P05129 1/20 0.52
PRKCB P05771 1/20 0.52
PRKCA P17252 1/20 0.52
PRKACA P17612 1/20 0.52
PRKACG P22612 1/20 0.52
PRKACB P22694 1/20 0.52
PRKCH P24723 1/20 0.52
PRKCI P41743 1/20 0.52
PRKCE Q02156 1/20 0.52
PRKCQ Q04759 1/20 0.52
PRKCZ Q05513 1/20 0.52
PRKCD Q05655 1/20 0.52
PRKD1 Q15139 1/20 0.52
PLA2G4A P47712 1/20 0.47
CDK4 P11802 4/20 0.46
CCND1 P24385 4/20 0.46
CDC7 O00311 1/20 0.46
CDK2 P24941 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29475118 1.00 BIRC5 (0.70) BIRC5PRKD3PRKCGPRKCBPRKCA
Hydrochloric Acid SCHEMBL3803742 0.98 BIRC5 (0.68) BIRC5PRKD3PRKCGPRKCBPRKCA
Phosphine SCHEMBL28297804 0.98 BIRC5 (0.68) BIRC5PRKD3PRKCGPRKCBPRKCA
Hydrochloric Acid SCHEMBL15066336 0.96 BIRC5 (0.66) BIRC5PRKD3PRKCGPRKCBPRKCA
Dimethylamine SCHEMBL5608192 0.92 BIRC5 (0.61) BIRC5PRKD3PRKCGPRKCBPRKCA
Aniline SCHEMBL22656869 0.90 BIRC5 (0.59) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL5792785 0.87 BIRC5 (0.67) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL13242029 0.86 BIRC5 (0.71) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL11910172 0.86 BIRC5 (0.60) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL10153905 0.86 BIRC5 (0.64) BIRC5PRKD3PRKCGPRKCBPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121569944-A Shepherd's purse essence and preparation method and application thereof 江西省华宝孔雀食品科技发展有限公司 2026-02-27 CN claimed
US-12405533-B2 Resist underlayer film-forming composition containing substituted crosslinkable compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2025-09-02 US claimed
US-20250231489-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2025-07-17 US claimed
CN-119998731-A Composition for forming resist underlayer film 日产化学株式会社 2025-05-13 CN claimed
US-20250128238-A1 SEPARATION MEDIA CONTAINING DYES DONALDSON COMPANY, INC. 2025-04-24 US claimed
CN-119798163-A New continuous carbamazepine preparation process 浙江工业大学 2025-04-11 CN claimed
CN-119674209-A PVDF-PMMA-based polymer electrolyte membrane and preparation method and application thereof 山东创鲁先进电池科技有限公司 2025-03-21 CN claimed
CN-119143678-A Fluorescent molecule for rapidly measuring excitation light spot size and light intensity distribution and preparation method thereof 中国科学院化学研究所 2024-12-17 CN claimed
CN-118666731-A 2-Phenylindole derivative and preparation method and application thereof 东南大学 2024-09-20 CN claimed
CN-118561843-A Preparation method of N- (2- (indole-1-yl) phenyl) benzenesulfonamide compound 青岛科技大学 2024-08-30 CN claimed
EP-0838527-A1 Method for measuring the concentration of polynucleotides Kyoto Daiichi Kagaku Co., Ltd. (JP) 1998-04-29 EP claimed
US-5703087-A PSYCHOLOGICAL DISORDERS H. LUNDBECK A/S (DK) 1997-12-30 US claimed
WO-1996041185-A9 METHODS AND COMPOSITIONS FOR BINDING ENDOTOXINS 1997-05-15 WO claimed
EP-0726898-A1 PHENYLINDOLE COMPOUNDS H. LUNDBECK A/S (DK) 1996-08-21 EP claimed
CN-1114662-A Stabilized flexible PVC CIBA GEIGY AG (CH) 1996-01-10 CN claimed
WO-1995012591-A1 PHENYLINDOLE COMPOUNDS H. LUNDBECK A/S (DK) 1995-05-11 WO claimed
EP-0214743-B1 USE OF QUINOLINE DERIVATIVES IN THE MANUFACTURE OF MEDICAMENTS FOR THE TREATMENT OF CEREBROVASCULAR DISORDERS AND CEREBRAL SENILITY BEECHAM GROUP PLC (GB) 1993-05-12 EP claimed
US-4808619-A HYPOTENSIVE AGENT, COGNITION ACTIVATOR BEECHAM GROUP P.L.C. (GB) 1989-02-28 US claimed
US-4558048-A Method of treating diarrhoea using indole compounds PFIZER INC. (US) 1985-12-10 US claimed
US-4330456-A Continuous process for producing a finely divided aqueous disperson of a homogeneous phase of at least one fusible solid ingredient CHLOE CHIMIE (FR) 1982-05-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12405533-B2 Resist underlayer film-forming composition containing substituted crosslinkable compound RAD51, RER1, ADH1A BIRC5 3265/4885PRKD3 4424/4885PRKCG 4276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.