Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 1.00 |
| ▸ | LMNA | P02545 | 7/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 6/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 3/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | MAOA | P21397 | 1/20 | 1.00 |
| ▸ | ESR1 | P03372 | 9/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.70 |
| ▸ | ACHE | P22303 | 1/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.67 |
| ▸ | SHBG | P04278 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lynestrenol SCHEMBL37816 | 1.00 | PGR (1.00) | PGRLMNACYP3A4CYP2C19ALDH1A1 | |
| Lynestrenol SCHEMBL9699960 | 1.00 | PGR (1.00) | PGRLMNACYP3A4CYP2C19ALDH1A1 | |
| Lynestrenol SCHEMBL11575942 | 0.99 | PGR (0.98) | PGRLMNACYP3A4CYP2C19ALDH1A1 | |
| Ethinyl Estradiol SCHEMBL9102012 | 0.87 | ESR1 (0.75) | PGRLMNACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL21807745 | 0.84 | CYP2C19 (0.74) | PGRLMNACYP3A4CYP2C19ALDH1A1 | |
| Cingestol SCHEMBL12178106 | 0.84 | CYP3A4 (0.72) | PGRLMNACYP3A4CYP2C19ALDH1A1 | |
| Cingestol SCHEMBL282508 | 0.84 | CYP3A4 (0.72) | PGRLMNACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL11858237 | 0.83 | PGR (0.71) | PGRLMNACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL30140942 | 0.83 | PGR (0.71) | PGRLMNACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL11858232 | 0.83 | PGR (0.71) | PGRLMNACYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014172616-A2 | METHODS, COMPOSITIONS AND KITS FOR PROMOTING MOTOR NEURON SURVIVAL AND TREATING AND DIAGNOSING NEURODEGENERATIVE DISORDERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-10-23 | — | — | WO | disclosed |