Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TNKS | O95271 | 2/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11949816 | 1.00 | MAPK10 (0.53) | MAPK10HSD17B10TSHRLMNAHPGD | |
| SCHEMBL11949702 | 0.94 | MAPK10 (0.48) | MAPK10HSD17B10TSHRLMNAHPGD | |
| SCHEMBL11949810 | 0.93 | MAPK10 (0.57) | MAPK10HSD17B10TSHRLMNAHPGD | |
| SCHEMBL11949794 | 0.88 | MAPK10 (0.54) | MAPK10HSD17B10TSHRLMNAHPGD | |
| SCHEMBL11949802 | 0.86 | MAPK10 (0.51) | MAPK10HSD17B10TSHRLMNAHPGD | |
| SCHEMBL11949820 | 0.85 | MAPK10 (0.52) | MAPK10HSD17B10TSHRLMNAHPGD | |
| SCHEMBL11949790 | 0.84 | MAPK10 (0.51) | MAPK10HSD17B10TSHRLMNAHPGD | |
| SCHEMBL11893959 | 0.81 | MAPK10 (0.66) | MAPK10HSD17B10TSHRLMNAHPGD | |
| SCHEMBL11893533 | 0.81 | SMN1; SMN2 (0.50) | MAPK10HSD17B10TSHRLMNAHPGD | |
| SCHEMBL1667965 | 0.81 | MAPK10 (0.66) | MAPK10HSD17B10TSHRLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865704-B2 | Wnt pathway antagonists | SIENA BIOTECH S.P.A. (IT) | 2014-10-21 | — | — | US | disclosed |
| US-8865704-B2 | Wnt pathway antagonists | SIENA BIOTECH S.P.A. (IT) | 2014-10-21 | — | — | US | disclosed |