Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11949810 | 0.90 | MAPK10 (0.57) | MAPK10HSD17B10LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11949816 | 0.86 | MAPK10 (0.53) | MAPK10HSD17B10LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL16181129 | 0.86 | MAPK10 (0.53) | MAPK10HSD17B10LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11949794 | 0.85 | MAPK10 (0.54) | MAPK10HSD17B10LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11949820 | 0.82 | MAPK10 (0.52) | MAPK10HSD17B10LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11949790 | 0.81 | MAPK10 (0.51) | MAPK10HSD17B10LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11949702 | 0.81 | MAPK10 (0.48) | MAPK10HSD17B10LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11893533 | 0.79 | SMN1; SMN2 (0.50) | MAPK10HSD17B10LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11893959 | 0.79 | MAPK10 (0.66) | MAPK10HSD17B10LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1667965 | 0.79 | MAPK10 (0.66) | MAPK10HSD17B10LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865704-B2 | Wnt pathway antagonists | SIENA BIOTECH S.P.A. (IT) | 2014-10-21 | — | — | US | disclosed |
| US-20120196851-A1 | WNT PATHWAY ANTAGONISTS | SIENA BIOTECH S.P.A. (IT) | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196851-A1 | WNT PATHWAY ANTAGONISTS | WNT1, WNT3A, CTNNB1 | MAPK10 231/4885HSD17B10 2237/4885LMNA 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.