Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9939989 | 0.83 | PTGES (0.50) | PTGES | |
| SCHEMBL9939853 | 0.72 | PTGES (0.72) | PTGES | |
| SCHEMBL9939828 | 0.71 | PTGES (0.80) | PTGES | |
| SCHEMBL9939858 | 0.71 | PTGES (0.73) | PTGES | |
| SCHEMBL9939850 | 0.71 | PTGES (0.80) | PTGES | |
| SCHEMBL9939925 | 0.71 | PTGES (0.71) | PTGES | |
| SCHEMBL9939932 | 0.71 | PTGES (0.71) | PTGES | |
| SCHEMBL9939921 | 0.70 | PTGES (0.72) | PTGES | |
| SCHEMBL9939873 | 0.70 | PTGES (0.54) | PTGES | |
| SCHEMBL9899133 | 0.70 | PTGES (0.67) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649052-B1 | 2-AMINOBENZIMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INT (DE) | 2014-10-22 | — | — | EP | disclosed |