Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.51 |
| ▸ | POLB | P06746 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.46 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.46 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3493549 | 0.87 | ALDH1A1 (0.55) | ALDH1A1TDP1POLBMAPTKMT2A | |
| SCHEMBL3491247 | 0.86 | MAPT (0.54) | ALDH1A1TDP1POLBMAPTKMT2A | |
| SCHEMBL3494773 | 0.83 | TDP1 (0.56) | ALDH1A1TDP1POLBMAPTKMT2A | |
| SCHEMBL3493776 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TDP1POLBMAPTKMT2A | |
| SCHEMBL3490750 | 0.81 | ALDH1A1 (0.55) | ALDH1A1TDP1POLBMAPTKMT2A | |
| SCHEMBL3492123 | 0.81 | MAPT (0.57) | ALDH1A1TDP1POLBMAPTKMT2A | |
| SCHEMBL14650893 | 0.80 | MAPT (0.58) | ALDH1A1TDP1POLBMAPTKMT2A | |
| SCHEMBL3492779 | 0.79 | MAPT (0.52) | ALDH1A1TDP1POLBMAPTKMT2A | |
| SCHEMBL3490623 | 0.78 | KMT2A (0.59) | ALDH1A1TDP1POLBMAPTKMT2A | |
| SCHEMBL3494524 | 0.78 | POLB (0.54) | ALDH1A1TDP1POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908765-B1 | THIENOPYRIMIDINE DERIVATIVE | ASKA PHARM CO LTD (JP) | 2014-10-22 | — | — | EP | disclosed |