SCHEMBL16182136

SCHEMBL16182136

c1ccc(-c2ccccc2-c2ccccc2-c2ccccc2-c2ccccc2-c2cccc3c2oc2ccccc23)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.57
GGPS1 O95749 1/20 0.46
PRKDC P78527 7/20 0.45
PIK3CD O00329 1/20 0.44
PIK3CB P42338 1/20 0.44
MEN1 O00255 1/20 0.42
CSF1R P07333 1/20 0.42
PDGFRB P09619 1/20 0.42
MAPT P10636 1/20 0.42
KIT P10721 1/20 0.42
FLT3 P36888 1/20 0.42
KMT2A Q03164 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
PTGES2 Q9H7Z7 1/20 0.42
CDC14B O60729 1/20 0.41
CDC14A Q9UNH5 1/20 0.41
ATM Q13315 1/20 0.40
AHR P35869 1/20 0.40
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16182148 1.00 ALOX5 (0.57) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL16182153 1.00 ALOX5 (0.57) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL15195381 0.93 ALOX5 (0.51) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL21431853 0.93 ALOX5 (0.59) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL11712766 0.92 ALOX5 (0.63) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL23597275 0.92 ALOX5 (0.50) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL27341248 0.92 ALOX5 (0.52) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL26750759 0.91 ALOX5 (0.59) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL431876 0.91 ALOX5 (0.66) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL27341389 0.91 ALOX5 (0.51) ALOX5GGPS1PRKDCPIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993127-B2 Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-31 US disclosed
EP-2428512-B1 Fluorene compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LAB (JP) 2014-10-22 EP disclosed