SCHEMBL16182152

SCHEMBL16182152

c1ccc2c(c1)-c1ccccc1C2(c1ccc(-c2ccc(-c3cccc4c3sc3ccccc34)cc2)cc1)c1ccc(-c2ccc(-c3cccc4c3sc3ccccc34)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.52
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
OPRK1 P41145 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PARP14 Q460N5 1/20 0.40
PRKDC P78527 6/20 0.37
GPR3 P46089 1/20 0.36
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
PIK3CD O00329 2/20 0.33
PIK3CB P42338 2/20 0.33
BRD4 O60885 1/20 0.33
PIK3CA P42336 1/20 0.33
MTOR P42345 1/20 0.33
PIK3CG P48736 1/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL438766 1.00 ALOX5 (0.52) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL371197 0.99 ALOX5 (0.54) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL440707 0.97 ALOX5 (0.50) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL437565 0.97 ALOX5 (0.50) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL437557 0.96 ALOX5 (0.51) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL328681 0.96 ALOX5 (0.51) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL440705 0.91 ALOX5 (0.48) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL440083 0.91 ALOX5 (0.53) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL17804847 0.89 ALOX5 (0.43) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL17126543 0.89 ALOX5 (0.43) ALOX5MEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9564597-B2 Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-02-07 US disclosed
US-9564597-B2 Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-02-07 US disclosed
US-8993127-B2 Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-31 US disclosed
US-8993127-B2 Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-31 US disclosed
EP-2428512-B1 Fluorene compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LAB (JP) 2014-10-22 EP disclosed