Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283198 | 0.80 | ATM (0.50) | MAOAMAOBCTSLBRD4NPC1 | |
| SCHEMBL328562 | 0.74 | MAOA (0.49) | MAOAMAOBCTSLBRD4NPC1 | |
| SCHEMBL28861070 | 0.73 | ESR1 (0.35) | TDP1L3MBTL1MAPTHTT | |
| SCHEMBL19789071 | 0.73 | PARP1 (0.45) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL22172116 | 0.70 | ATM (0.59) | BRD4NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL17125443 | 0.70 | — | — | |
| SCHEMBL3838580 | 0.70 | PARP1 (0.63) | MAOAMAOBCTSLBRD4TDP1 | |
| SCHEMBL328648 | 0.69 | HDAC8 (0.60) | MAOAMAOBTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL40538 | 0.68 | ATM (0.71) | MAOAMAOBBRD4NPC1RAB9A | |
| SCHEMBL18562454 | 0.68 | CHRNB4 (0.40) | MAOAMAOBNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428512-B1 | Fluorene compound, light-emitting element, light-emitting device, electronic device and lighting device | SEMICONDUCTOR ENERGY LAB (JP) | 2014-10-22 | — | — | EP | disclosed |