Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 3/20 | 0.97 |
| ▸ | MEN1 | O00255 | 6/20 | 0.90 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.90 |
| ▸ | HTT | P42858 | 5/20 | 0.90 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.90 |
| ▸ | PKM | P14618 | 4/20 | 0.90 |
| ▸ | NPC1 | O15118 | 4/20 | 0.90 |
| ▸ | RAB9A | P51151 | 4/20 | 0.90 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.90 |
| ▸ | POLB | P06746 | 3/20 | 0.90 |
| ▸ | NSD2 | O96028 | 2/20 | 0.90 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.90 |
| ▸ | APP | P05067 | 5/20 | 0.76 |
| ▸ | CHAT | P28329 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | THRB | P10828 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14984145 | 1.00 | RAD52 (0.97) | RAD52MEN1KMT2AHTTNPSR1 | |
| SCHEMBL13766059 | 0.84 | CHAT (0.79) | RAD52MEN1KMT2AHTTNPSR1 | |
| SCHEMBL13043736 | 0.83 | RAD52 (0.70) | RAD52MEN1KMT2AHTTNPSR1 | |
| SCHEMBL13043737 | 0.83 | RAD52 (0.70) | RAD52MEN1KMT2AHTTNPSR1 | |
| SCHEMBL10104148 | 0.82 | RAD52 (0.68) | RAD52MEN1KMT2AHTTNPSR1 | |
| SCHEMBL14700346 | 0.82 | CHAT (0.77) | RAD52MEN1KMT2AHTTNPSR1 | |
| SCHEMBL4626049 | 0.82 | CHAT (0.77) | RAD52MEN1KMT2AHTTNPSR1 | |
| SCHEMBL4626052 | 0.82 | CHAT (0.77) | RAD52MEN1KMT2AHTTNPSR1 | |
| SCHEMBL1245826 | 0.82 | CHAT (0.77) | RAD52MEN1KMT2AHTTNPSR1 | |
| SCHEMBL13428296 | 0.82 | MEN1 (0.97) | RAD52MEN1KMT2AHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10024863-B2 | Methods for dye selection for protein melt temperature determinations | Life Technologies Corporation (US) | 2018-07-17 | — | — | US | disclosed |
| US-10024863-B2 | Methods for dye selection for protein melt temperature determinations | Life Technologies Corporation (US) | 2018-07-17 | — | — | US | disclosed |
| US-20140315190-A1 | METHODS FOR DYE SELECTION FOR PROTEIN MELT TEMPERATURE DETERMINATIONS | Life Technologies Corporation | 2014-10-23 | — | — | US | disclosed |
| US-20140315190-A1 | METHODS FOR DYE SELECTION FOR PROTEIN MELT TEMPERATURE DETERMINATIONS | Life Technologies Corporation | 2014-10-23 | — | — | US | disclosed |