Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | KDM4A | O75164 | 3/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20380419 | 0.91 | MEN1 (0.57) | INSRMEN1KMT2ARAB9APOLB | |
| SCHEMBL14984184 | 0.80 | KDM4A (0.58) | INSRMEN1KMT2ARAB9ALMNA | |
| SCHEMBL14562210 | 0.80 | ACHE (0.71) | INSRMEN1KMT2ARAB9APOLB | |
| SCHEMBL16183112 | 0.79 | KDM4A (0.62) | INSRMEN1KMT2ARAB9AHTT | |
| SCHEMBL18102243 | 0.79 | KDM4A (0.62) | INSRMEN1KMT2ARAB9AHTT | |
| SCHEMBL10035998 | 0.79 | MEN1 (0.72) | INSRMEN1KMT2ARAB9APOLB | |
| SCHEMBL30670643 | 0.79 | APP (0.42) | MEN1KMT2ARAB9APOLBLMNA | |
| SCHEMBL18102271 | 0.78 | APP (0.44) | INSRMEN1KMT2ARAB9ALMNA | |
| SCHEMBL13629539 | 0.78 | CHRM2 (0.61) | INSRMEN1KMT2AHTTBLM | |
| SCHEMBL455654 | 0.77 | CHRM2 (0.52) | INSRMEN1KMT2ARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140315190-A1 | METHODS FOR DYE SELECTION FOR PROTEIN MELT TEMPERATURE DETERMINATIONS | Life Technologies Corporation | 2014-10-23 | — | — | US | disclosed |