Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 4/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16183111 | 0.95 | APP (0.57) | APPMAPTALDH1A1SMN1; SMN2GLA | |
| SCHEMBL5676615 | 0.87 | CHRM2 (0.61) | APPMAPTALDH1A1SMN1; SMN2GLA | |
| SCHEMBL5676626 | 0.87 | CHRM2 (0.61) | APPMAPTALDH1A1SMN1; SMN2GLA | |
| SCHEMBL83586 | 0.87 | CHRM2 (0.57) | APPMAPTALDH1A1SMN1; SMN2GLA | |
| Iodide SCHEMBL4959850 | 0.86 | CHRM2 (0.60) | APPMAPTALDH1A1SMN1; SMN2GLA | |
| Iodide SCHEMBL4959859 | 0.86 | CHRM2 (0.60) | APPMAPTALDH1A1SMN1; SMN2GLA | |
| SCHEMBL5128472 | 0.83 | CHRM2 (0.56) | APPMAPTALDH1A1SMN1; SMN2GLA | |
| SCHEMBL42898 | 0.83 | CHRM2 (0.56) | APPMAPTALDH1A1SMN1; SMN2GLA | |
| SCHEMBL3054036 | 0.82 | CHRM2 (0.55) | APPMAPTALDH1A1SMN1; SMN2GLA | |
| SCHEMBL10340879 | 0.82 | CHRM2 (0.55) | APPMAPTALDH1A1SMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10024863-B2 | Methods for dye selection for protein melt temperature determinations | Life Technologies Corporation (US) | 2018-07-17 | — | — | US | disclosed |
| US-20140315190-A1 | METHODS FOR DYE SELECTION FOR PROTEIN MELT TEMPERATURE DETERMINATIONS | Life Technologies Corporation | 2014-10-23 | — | — | US | disclosed |