Iodide

Iodide

SCHEMBL4959859

CCCCN(CCCC)c1ccc(C=Cc2cc[n+](C)cc2)cc1.[I-]

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 2/20 0.60
CHRM3 known ✓ P20309 2/20 0.60
ACHE known ✓ P22303 2/20 0.43
CHRM2 P08172 2/20 0.60
CHRM4 P08173 2/20 0.60
CHRM5 P08912 2/20 0.60
ALDH1A1 P00352 3/20 0.58
MAPT P10636 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
MEN1 O00255 1/20 0.58
LMNA P02545 1/20 0.58
ALPG P10696 1/20 0.58
THRB P10828 1/20 0.58
HTT P42858 1/20 0.58
GFER P55789 1/20 0.58
KMT2A Q03164 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
KDM4A O75164 4/20 0.51
KDM2A Q9Y2K7 4/20 0.51
KDM4E B2RXH2 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL4959850 1.00 CHRM2 (0.60) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL5676615 0.98 CHRM2 (0.61) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL5676626 0.98 CHRM2 (0.61) CHRM2CHRM4CHRM5CHRM1CHRM3
Iodide SCHEMBL29489399 0.95 ALDH1A1 (0.57) CHRM2CHRM4CHRM5CHRM1CHRM3
Iodide SCHEMBL3954410 0.94 KDM4A (0.56) CHRM2CHRM4CHRM5CHRM1CHRM3
Iodide SCHEMBL554665 0.94 KDM4A (0.56) CHRM2CHRM4CHRM5CHRM1CHRM3
Iodide SCHEMBL28531710 0.94 KDM4A (0.56) CHRM2CHRM4CHRM5CHRM1CHRM3
Iodide SCHEMBL3954408 0.94 KDM4A (0.56) CHRM2CHRM4CHRM5CHRM1CHRM3
Iodide SCHEMBL187217 0.94 KDM4A (0.56) CHRM2CHRM4CHRM5CHRM1CHRM3
Iodide SCHEMBL21494443 0.94 KDM4A (0.56) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116715623-A Photothermal conversion eutectic material and preparation method and application thereof 汕头大学 2023-09-08 CN claimed
US-6770102-B1 AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS; DOES NOT REQUIRE OXIDIZING AGENT; BRILLIANCE; COLOR DEPTH; WIDE VARIETY OF SHADES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-08-03 US claimed
EP-3478792-B1 CHEMILUMINESCENT SUBSTRATES BECKMAN COULTER INC (US) 2023-12-13 EP disclosed
US-10703971-B2 Chemiluminescent substrates BECKMAN COULTER, INC. (US) 2020-07-07 US disclosed
US-20190161675-A1 CHEMILUMINESCENT SUBSTRATES BECKMAN COULTER, INC. (US) 2019-05-30 US disclosed
US-7322927-B2 Hybrid phthalocyanine derivatives and their uses BIOSITE, INC. (US) 2008-01-29 US disclosed
US-20060228748-A1 Hybrid phthalocyanine derivatives and their uses BIOSITE INCORPORATED 2006-10-12 US disclosed
US-7083984-B2 Hybrid phthalocyanine derivatives and their uses BIOSITE, INC. (US) 2006-08-01 US disclosed
US-6964844-B1 Hybrid phthalocyanine derivatives and their uses BIOSITE, INC. (US) 2005-11-15 US disclosed
US-6635437-B2 Useful in methods for producing light and in assays for phosphatase enzymes and enzyme inhibitors and in assays employing enzyme-labeled specific binding pairs LUMIGEN, INC. 2003-10-21 US disclosed
EP-0819119-B1 COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES LUMIGEN INC (US) 2003-04-02 EP disclosed
US-6218137-B1 SENSITIVE QUANTITATIVE ANALYSIS USING COMPOUND HAVING A HETEROCYCLIC RING SYSTEM BEARING AN EXOCYCLIC CARBON-CARBON DOUBLE BOND WHICH IS SUBSTITUTED AT DISTAL CARBON WITH PHOSPHATE GROUP AND OXYGEN OR SULFUR GROUP LUMIGEN, INC. 2001-04-17 US disclosed
US-6139782-A A CHEMILUMINESCENT CONTAINING A HETEROCYCLIC RING GROUP AND AN ENOL PHOSPHATE GROUP WHICH REACT WITH OXYGEN UPON REMOVAL OF PHOSPHATE GROUP WITH A PHOSPHATASE ENZYME TO PRODUCE AN ENOLATE WHICH REACTS WITH TO PRODUCE CHEMILUMINOESCENCE LUMIGEN, INC. (US) 2000-10-31 US disclosed
US-6090571-A REACTING PHOSPHATASE WITH NITROGEN-CONTAINING HETEROCYCLIC RING SYSTEM HAVING AN ENOL PHOSPHATE GROUP, DETECTING THE CHEMILUMINESCENCE, AND RELATING TO AMOUNT OF ANALYTE LUMIGEN, INC. (US) 2000-07-18 US disclosed
US-6045727-A NITROGEN CONTAINING HETEROCYCLIC RING SYSTEM BEARING AN EXOCYCLIC CARBON-CARBON DOUBLE BOND. THE DOUBLE BOND IS FURTHER SUBSTITUTED AT THE DISTAL CARBON WITH A PHOSPHATE GROUP AND AN OXYGEN OR SULFUR ATOM-CONTAINING GROUP. LUMIGEN, INC. (US) 2000-04-04 US disclosed
EP-0819119-A4 COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES LUMIGEN INC (US) 1999-04-14 EP disclosed
EP-0820489-A1 HYBRID PHTHALOCYANINE DERIVATIVES AND THEIR USES BIOSITE DIAGNOSTICS INC. (US) 1998-01-28 EP disclosed
EP-0819119-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES LUMIGEN, INC. (US) 1998-01-21 EP disclosed
WO-1997026245-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES LUMIGEN, INC. (US) 1997-07-24 WO disclosed
WO-1996029367-A1 HYBRID PHTHALOCYANINE DERIVATIVES AND THEIR USES BIOSITE DIAGNOSTICS INCORPORATED (US) 1996-09-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060228748-A1 Hybrid phthalocyanine derivatives and their uses UACA, PHAX, PTBP1 CHRM1 4771/4885CHRM3 4828/4885ACHE 4102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.