Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.50 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655879 | 0.77 | CYP2C19 (0.56) | CYP2C19HDAC1LMNAHDAC3HDAC4 | |
| SCHEMBL28748361 | 0.77 | CYP2C19 (0.67) | CYP2C19HDAC1LMNAHDAC3HDAC4 | |
| SCHEMBL30583099 | 0.77 | CYP2C19 (0.56) | CYP2C19HDAC1LMNAHDAC3HDAC4 | |
| SCHEMBL6067666 | 0.77 | CYP2C19 (0.67) | CYP2C19HDAC1LMNAHDAC3HDAC4 | |
| SCHEMBL3340845 | 0.77 | MAOB (0.50) | CYP2C19HDAC1LMNAHDAC3HDAC4 | |
| SCHEMBL18903348 | 0.77 | MAOB (0.50) | CYP2C19HDAC1LMNAHDAC3HDAC4 | |
| SCHEMBL27549817 | 0.75 | CYP2C19 (0.55) | CYP2C19HDAC1LMNAHDAC3HDAC4 | |
| SCHEMBL831183 | 0.75 | CYP2C19 (0.55) | CYP2C19HDAC1LMNAHDAC3HDAC4 | |
| SCHEMBL21327076 | 0.75 | CYP2C19 (0.50) | CYP2C19HDAC1LMNAHDAC3HDAC4 | |
| SCHEMBL3906269 | 0.74 | CYP2C19 (0.53) | CYP2C19HDAC1LMNAHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923578-B2 | Prevent sagging of skin; luster ; amidation of 3-(4-hydroxyphenyl)propionic acid with ammonia using 4-nitrophenol in ethyl acetateand dicyclohexylcarbodiimide; stirring ; precipitation dicyclohexylurea; filtration under vacuum | INSTYTUT CHEMII BIOORGANICZNEJ PAN (PL) | 2011-04-12 | — | — | US | disclosed |
| US-20080249334-A1 | Method of Manufacturing 3-(4-Hydroxyphenyl)Propanoic Acid Amide, Its Application in the Manufacture of Anti-Aging Compositions and Anti-Aging Composition | INSTYTUT CHEMII BIOORGANICZNEJ PAN (PL) | 2008-10-09 | — | — | US | disclosed |
| EP-1971571-A2 | A METHOD OF MANUFACTURING 3-(4-HYDROXYPHENYL)PROPANOIC ACID AMIDE, ITS APPLICATION IN THE MANUFACTURE OF ANTI-AGING COMPOSITIONS AND AN ANTI-AGING COMPOSITION | Instytut Chemii Bioorganicznej PAN (PL) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007046721-A2 | A METHOD OF MANUFACTURING 3-(4-HYDROXYPHENYL)PROPANOIC ACID AMIDE, ITS APPLICATION IN THE MANUFACTURE OF ANTI-AGING COMPOSITIONS AND AN ANTI-AGING COMPOSITION | INSTYTUT CHEMII BIOORGANICZNEJ PAN (PL) | 2007-04-26 | — | — | WO | disclosed |