SCHEMBL16187951

SCHEMBL16187951

CC(=O)NCCCNC(=O)C(CCCCN)NC(=O)C(N)Cc1cnc[nH]1

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SLC15A2 Q16348 1/20 0.54
▸ GHSR Q92847 1/20 0.47
▸ NLN Q9BYT8 2/20 0.47
▸ SIRT6 Q8N6T7 1/20 0.46
▸ SIRT1 Q96EB6 1/20 0.46
▸ QPCT Q16769 1/20 0.46
▸ QPCTL Q9NXS2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16185925 0.92 SLC15A2 (0.54) SLC15A2GHSRNLN
SCHEMBL16187205 0.84 NLN (0.47) SLC15A2NLN
SCHEMBL27706632 0.83 SLC15A2 (0.74) SLC15A2GHSR
SCHEMBL30911281 0.83 SLC15A2 (0.74) SLC15A2GHSR
SCHEMBL27687339 0.81 SLC15A2 (0.63) SLC15A2GHSR
SCHEMBL29774683 0.78 SLC15A2 (0.72) SLC15A2GHSR
SCHEMBL29014876 0.78 SLC15A2 (0.63) SLC15A2GHSR
SCHEMBL29774690 0.78 SLC15A2 (0.72) SLC15A2GHSR
SCHEMBL30409074 0.77 SLC15A2 (0.71) SLC15A2GHSR
SCHEMBL28027302 0.77 SLC15A2 (0.71) SLC15A2GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9359282-B2 Functionalized nanodiamonds as delivery platforms for nucleic acids UNIVERSITY OF SASKATCHEWAN (CA) 2016-06-07 — — US disclosed
US-9012838-B2 Covalently functionalized nanodiamond-based MALDI matrices and methods of use thereof UNIVERSITY OF SASKATCHEWAN (CA) 2015-04-21 — — US disclosed
US-20140312218-A1 COVALENTLY FUNCTIONALIZED NANODIAMOND-BASED MALDI MATRICES AND METHODS OF USE THEREOF UNIVERSITY OF SASKATCHEWAN (CA) 2014-10-23 — — US disclosed
US-20140314850-A1 FUNCTIONALIZED NANODIAMONDS AS DELIVERY PLATFORMS FOR NUCLEIC ACIDS UNIVERSITY OF SASKATCHEWAN (CA) 2014-10-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140312218-A1 COVALENTLY FUNCTIONALIZED NANODIAMOND-BASED MALDI MATRICES AND METHODS OF USE THEREOF ITGA2B, MMP2, ITGAV SLC15A2 3731/4885GHSR 4785/4885NLN 145/4885
US-20140314850-A1 FUNCTIONALIZED NANODIAMONDS AS DELIVERY PLATFORMS FOR NUCLEIC ACIDS ANXA7, ANXA6, NSUN2 SLC15A2 1509/4885GHSR 4731/4885NLN 104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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