Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 16/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 15/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 10/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | ITGB8 | P26012 | 3/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | MC5R | P33032 | 1/20 | 0.43 |
| ▸ | MC3R | P41968 | 1/20 | 0.43 |
| ▸ | MC1R | Q01726 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16188466 | 0.94 | ITGB3 (0.48) | ITGAVITGB3ITGB1ITGA5ITGB5 | |
| SCHEMBL16177741 | 0.83 | ITGB3 (0.61) | ITGAVITGB3ITGB1ITGA5ITGB5 | |
| SCHEMBL14885782 | 0.83 | ITGB3 (0.61) | ITGAVITGB3ITGB1ITGA5ITGB5 | |
| SCHEMBL18970023 | 0.81 | ITGB3 (0.51) | ITGAVITGB3ITGB1ITGA5ITGB5 | |
| SCHEMBL29726666 | 0.79 | ITGB3 (0.54) | ITGAVITGB3ITGB5ITGA2B | |
| SCHEMBL22793231 | 0.79 | ITGB3 (0.47) | ITGAVITGB3ITGB1ITGA5ITGB5 | |
| SCHEMBL24253221 | 0.79 | ITGB3 (0.49) | ITGAVITGB3ITGB5ITGA2B | |
| SCHEMBL16135323 | 0.77 | ITGB3 (0.54) | ITGAVITGB3ITGB1ITGA5ITGB5 | |
| SCHEMBL8321039 | 0.77 | ITGB3 (0.56) | ITGAVITGB3ITGB1ITGA5ITGB5 | |
| SCHEMBL29568996 | 0.76 | ITGB3 (0.51) | ITGAVITGB3ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9476883-B2 | Cellular recognition conjugates and methods of use for the histological analysis of cancer tissue using MALDI-MS imaging | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2016-10-25 | — | — | US | disclosed |
| US-20140315220-A1 | CELLULAR RECOGNITION CONJUGATES AND METHODS OF USE FOR THE HISTOLOGICAL ANALYSIS OF CANCER TISSUE USING MALDI-MS IMAGING | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2014-10-23 | — | — | US | disclosed |