Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 19/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21140799 | 1.00 | CYP19A1 (0.65) | CYP19A1SRD5A2 | |
| SCHEMBL16188740 | 1.00 | CYP19A1 (0.65) | CYP19A1SRD5A2 | |
| SCHEMBL16189915 | 1.00 | CYP19A1 (0.65) | CYP19A1SRD5A2 | |
| SCHEMBL16188739 | 1.00 | CYP19A1 (0.65) | CYP19A1SRD5A2 | |
| SCHEMBL5925780 | 0.86 | CYP19A1 (0.67) | CYP19A1SRD5A2 | |
| SCHEMBL21140790 | 0.85 | CYP19A1 (0.65) | CYP19A1 | |
| SCHEMBL16188693 | 0.85 | CYP19A1 (0.65) | CYP19A1 | |
| SCHEMBL17209920 | 0.81 | SHBG (0.67) | CYP19A1SRD5A2 | |
| SCHEMBL20326142 | 0.81 | CYP19A1 (0.58) | CYP19A1 | |
| SCHEMBL8495289 | 0.79 | CYP19A1 (1.00) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014169833-A9 | 19-NOR C3,3-DISUBSTITUTED C21-N-PYRAZOLYL STEROIDS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. (US) | 2016-03-03 | — | — | WO | disclosed |
| WO-2014169833-A1 | 19-NOR C3,3-DISUBSTITUTED C21-N-PYRAZOLYL STEROIDS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. (US) | 2014-10-23 | — | — | WO | disclosed |