Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | ATIC | P31939 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | MPL | P40238 | 2/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHAT | P28329 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446869 | 0.84 | TTR (0.50) | TTRCYP1A2PGAM1AURKAAURKB | |
| SCHEMBL7784949 | 0.81 | TTR (0.48) | TTRCYP1A2PGAM1AURKAAURKB | |
| SCHEMBL9636011 | 0.80 | TTR (0.44) | TTRCYP1A2PGAM1AURKAAURKB | |
| SCHEMBL332245 | 0.79 | TSHR (0.44) | TTRCYP1A2PGAM1AURKAAURKB | |
| SCHEMBL5346252 | 0.78 | MYC (0.44) | TTRCYP1A2AURKAAURKBMYC | |
| SCHEMBL8517108 | 0.77 | PGAM1 (0.47) | TTRCYP1A2PGAM1AURKAAURKB | |
| SCHEMBL29470806 | 0.77 | CDK2 (0.50) | TTRCYP1A2PGAM1AURKAAURKB | |
| SCHEMBL114040 | 0.77 | CDK2 (0.50) | TTRCYP1A2PGAM1AURKAAURKB | |
| Potassium SCHEMBL8940728 | 0.76 | CDK2 (0.48) | TTRCYP1A2PGAM1AURKAAURKB | |
| SCHEMBL9509847 | 0.76 | CDK2 (0.48) | TTRCYP1A2PGAM1AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019169478-A1 | TREATMENT OF PROTEIN AGGREGATION DISEASES USING N,N,N-TRIMETHYLCHITOSAN | OVENSA INC. (CA) | 2019-09-12 | — | — | WO | claimed |
| WO-2019169478-A1 | TREATMENT OF PROTEIN AGGREGATION DISEASES USING N,N,N-TRIMETHYLCHITOSAN | OVENSA INC. (CA) | 2019-09-12 | — | — | WO | disclosed |
| WO-2012027794-A2 | METHOD OF TREATMENT AND AGENTS USEFUL FOR SAME | THE MENTAL HEALTH RESEARCH INSTITUTE OF VICTORIA (AU) | 2012-03-08 | — | — | WO | disclosed |
| EP-0460679-B1 | Endothelin antagonistic peptide derivatives | BANYU PHARMA CO LTD (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5691315-A | CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5470833-A | Vasodilators, bronchodilators | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5444152-A | Vasolidator or bronchodilator | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| EP-0460679-A2 | Endothelin antagonistic peptide derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |